1.) What's your current prednisone dosage?
2.) Had you considered adding in oral and rectal-route mesalamines (lialda/apriso/delzicol and rowasa)?
3.) Have you considered adding an immunomodulator as a bridge (methotrexate is fast working)? Or are they a no, no due to the past cancer issue? I know 6mp/imuran sometimes isn't recommended for those who've had skin cancer in the past (some have had melanoma relapses due to 6mp/imuran). Not sure if that applies to methotrexate as well. Methotrexate isn't as common as 6mp/imuran for UC patients though!
JGS 75 said...
If by some chance the insurance were to approve it, what kind of havoc would having two biologics in your system at the same time cause?
I don't believe it has been studied. The goal of biologics is to slightly reduce the immune system's ability to request, initiate, and complete an attack. Remicade mutes the request/signal for an attack, and entyvio limits the completion of the attack. You'd just want to make sure you aren't suppressing the immune system too much with dual biologics (I don't know if it would, but that would be the primary concern). As you still have infections, colds, flus, and other things to contend with in our everyday lives.
4.) Your doctor can submit a request to your insurance to see what happens, your situation is unique with the limitations of a prior cancer so maybe it would be considered differently perhaps? I would expect an initial denial. He can appeal and sometimes they are approved.
5.) Has your doctor done remicade as a bridge to entyvio before? What was the results? How many patients? I would ask questions like that. And I'm curious about
those answers too!
Moderator Ulcerative Colitis
John, 39, UC Proctosigmoiditis
Rx: Remicade @5mgs/kg/6wks; daily 75mgs 6MP, 4.8g generic-Lialda, and rowasaA semi-finalist in the Olympic 15-meter bathroom-sprint. Aimed for the gold but just ended up getting brown...
Post Edited (iPoop) : 1/12/2018 6:23:45 AM (GMT-7)