Heart flutters and mezavant?

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Regular Member

Date Joined Feb 2005
Total Posts : 239
   Posted 1/11/2018 8:47 PM (GMT -6)   
Hello everyone...just wondering if anyone might have experienced this? UC wants to act up again so I started mezavant again Jan 3 to 8, 2018. I felt flutters or flipflops on occasion at least 2x per day since the second day I started med. . I don't know if because overtired or if because of UC acting up and the Vegas nerve reaction or a reaction to mezavant? The last time i took mezavant was Jan 8 and I was awakened from sleep with my heart flip-flopping. So I stopped taking it to see what happens and havent had a heart flutter yet.

So needless to say, I am a bit anxious to take it again but I probably should to keep UC from getting out of hand. My bmS a bit blood in it but only about 1x per day and mostly formed.

Hmmm? Suggestions would be so helpful... wink

Regular Member

Date Joined Jan 2017
Total Posts : 394
   Posted 1/11/2018 10:19 PM (GMT -6)   
I dont know if there is a specific concern level with the medicine itself, but I have always had some heart fluttering/flip flopping. It was the worst when I was pregnant with my third child. I actually wore a holter (I think that is what they call it) and the cardiologist did an ultrasound of my heart. He told me that my heart was very healthy, and not to worry about the flutters (some of which did show up.) Apparently, unless a heart doesn't come back to normal, it isn't a problem. I have had extra flutters from Prednisone and solumedrol, and nurses have assured me it's a normal reaction. Maybe ask your docter if there is a threshold where you should be concerned at so you can know what might still be in the range of normal.
36yr old mother of 3 Moderate Pancolitis 1/3/17. Hosp 1 week on Solumedrol, Delzicol. Apriso, pred, then switched to Balsazide 750 mg, and Uceris 9 mg 3 wks. Minor flare in August, flare since Oct 20. Acute pancreatitis from Balsalazide hosp. 2 days, Started Humira 12/15/17, 40 mg pred, waiting on Entyvio due to reaction Humira. Veg, gf, no cows milk, multi, cal-mag, Aroga, Purrium

Uniform Charlie
Veteran Member

Date Joined Jul 2015
Total Posts : 727
   Posted 1/12/2018 8:25 AM (GMT -6)   
Are you certain it is a heart flutter and not gas/indigestion?
Diagnosed Proctosigmoiditis (UC) February 2015
Current Meds: Lialda 1.2gm 2x daily, duloxetine, rowasa as needed

Forum Moderator

Date Joined Aug 2012
Total Posts : 13219
   Posted 1/12/2018 8:34 AM (GMT -6)   
Are you staying well hydrated? Dehydration can cause faster and louder. Flares can make staying hydrated a challenge due to the frequent diarrhea...
Moderator Ulcerative Colitis
, 39, UC Proctosigmoiditis
Rx: Remicade @5mgs/kg/6wks; daily 75mgs 6MP, 4.8g generic-Lialda, and rowasa

A semi-finalist in the Olympic 15-meter bathroom-sprint. Aimed for the gold but just ended up getting brown...

Serenity Now
Veteran Member

Date Joined Jan 2009
Total Posts : 2153
   Posted 1/12/2018 11:25 AM (GMT -6)   
Just to throw something else into the mix, I went through a period of heart flutters and only later realized it coincided with peri-menopause and p-m can be a cause. Interestingly I am now taking Mezavant and do not experience any heart flutters and when the flutters occured I was not on Mezavant.
Female, 51, Vancouver BC
Pancolitis: Currently in remission

Jan-Mar2009: Asacol HD. Resulted in severe joint pain and no discernible benefit.
May26-Sep4/2016: Mezavant 4800 mg
Sep5/2016 - : Mezavant 2400 mg

Elite Member

Date Joined May 2003
Total Posts : 30998
   Posted 1/12/2018 2:25 PM (GMT -6)   
Hi Kat, happy new year!

Were you a long time without any oral/rectal meds?
Get on rectal meds for sure...what were you using in the past?

What is the total dosage of the mezavant...1200? 2400? Do you take it at one time? Split?

*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma); Effexor XR 75mg (depression); Rosuvastatin 10mg (cholesterol); Telemesartin 80mg / Amlodipine 5mg (BP)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care + Genuine Health Advanced Gut Health 15 billion @ bedtime)
~Metamucil capsules 6 @ 2x daily with meals; Vitamin D 4500 IU
~URSO 500mg @ 2x daily for Primary Biliary Cholangitis
"TREAT (FROM)BOTH ENDS" worth it !!
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