A lot of these drugs reduce immune function, that is probably the biggest thing to look out for, infections... What are the antibiotics for? Which antibiotic?
After I got a debilitating infection on a combo of drugs, they told me I would have to take antibiotics as a preventative if I were to go on prednisone again while on biologics... I ended up having surgery, and I've been done with all the drugs for a few years. That said, it's pretty common for people to be on a biologic, and aza at the same time, and if there's a flare up on those drugs, they take steroids. Usually people don't take antibiotics, but some people have positive response to certain antibiotics, others have adverse reactions to antibiotics.
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From Sickly to UC Free
Give a man a fish and he will eat for a day; teach a man to fish and he will eat for a lifetime; give a man religion and he will die praying for a fish