How accurate is fecal calprotectin?

I’ve been on Humira since September, and I’ve been doing really well on it. I want to get pregnant soon, so my doctor ordered bloodwork and a stool test to check inflammatory markers. I did the bloodwork 2 weeks ago, everything came back within normal ranges, and I’m going to drop the stool sample off tomorrow.

How accurate is the fecal calprotectin at detecting inflammation? If it comes back within a normal range, can I feel confident that I’m in remission?

I know a colonoscopy is the best way to confirm remission, but I just had one in September and I’m not sure my insurance would cover another one this soon. I also have some anxiety over the thought of having another colonoscopy, as I’m positive the prep/procedure greatly exacerbated the flare and cdiff infection I had in September which resulted in being hospitalized.

What is everyone’s experience with this? Have you found the calprotectin results were accurate?

Thanks!

My range was so high, I have to retest

---

UC since '05, now in '15 Mayo Clinic say Chrons/colitis, U of M '17, ulcer in 30% of colon, of those ulcer 75% are ulcerated. No biologics work. Rethinking a game plan with doctor, whom I'm not impressed with.

Thanks for the feedback. I wish there was a more accurate, less invasive measure of inflammation.

iPoop, I think I had a calprotectin test when I first had symptoms in 2010, but I don’t remember the results of that test and whether or not they were consistent with the colonoscopy. I haven’t had a stool test since then.

Hopefully, I’ll have the results in a few days and will talk to my doctor about what everything means.

Thanks again!