Childhood physical, sexual abuse linked to ulcerative colitis

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Uniform Charlie
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Date Joined Jul 2015
Total Posts : 726
   Posted 3/12/2018 9:36 AM (GMT -6)   
Tough to deny the brain?gut connection.

A sad but interesting article:
/www.sciencedaily.com/releases/2015/08/150806160921.htm

"We found that one-quarter of adults with ulcerative colitis reported they had been physically abused during their childhood, compared to one in 10 of those without inflammatory bowel disease," said the study's lead author, Professor Esme Fuller-Thomson, who holds the Sandra Rotman Endowed Chair at University of Toronto's Factor-Inwentash Faculty of Social Work. "Similarly, the prevalence of childhood sexual abuse among those with ulcerative colitis was one in five versus one in 17 among those without the disease."

Investigators examined a representative sample of 21,852 community-dwelling Canadians aged 18 and over from the 2012 Canadian Community Health Survey -- Mental Health.

Diagnosed Proctosigmoiditis (UC) February 2015
Current Meds: Lialda 1.2gm 2x daily, duloxetine, rowasa as needed, Curcumin, VSL3 occasionally, One a Day Multi-Vitamin
Did SCD for about 2 years but lost willpower. Want to get back to it at some point.

quincy
Elite Member


Date Joined May 2003
Total Posts : 30976
   Posted 3/12/2018 12:31 PM (GMT -6)   
Interesting, but I'm not believing it as a cause.
To me, that's like saying boys who were sexually abused become gay.

q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma); Effexor XR 75mg (depression); Rosuvastatin 10mg (cholesterol); Telemesartin 80mg / Amlodipine 5mg (BP)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care + Genuine Health Advanced Gut Health 15 billion @ bedtime)
~Metamucil capsules 6 @ 2x daily with meals; Vitamin D 4500 IU
~URSO 500mg @ 2x daily for Primary Biliary Cholangitis
"TREAT (FROM)BOTH ENDS" worth it !!

Uniform Charlie
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Date Joined Jul 2015
Total Posts : 726
   Posted 3/12/2018 1:09 PM (GMT -6)   
I thought of that after I posted it, quincy. I don't know anything about these health surveys but maybe someone who is more likely to admit to physical/sexual abuse is also more likely to admit to having ulcerative colitis. Both are taboo subjects.

quincy
Elite Member


Date Joined May 2003
Total Posts : 30976
   Posted 3/12/2018 2:29 PM (GMT -6)   
Separate issues.....and dealt with accordingly. Studies are full of bs....at least one like this.

q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma); Effexor XR 75mg (depression); Rosuvastatin 10mg (cholesterol); Telemesartin 80mg / Amlodipine 5mg (BP)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care + Genuine Health Advanced Gut Health 15 billion @ bedtime)
~Metamucil capsules 6 @ 2x daily with meals; Vitamin D 4500 IU
~URSO 500mg @ 2x daily for Primary Biliary Cholangitis
"TREAT (FROM)BOTH ENDS" worth it !!

suchatravesty
Regular Member


Date Joined Dec 2017
Total Posts : 216
   Posted 3/12/2018 3:47 PM (GMT -6)   
Randomly, I was watching 60 minutes last night, and Oprah did a piece on ACE scores (Adverse Childhood Experiences) and how they translate into health outcomes and likelihood of victimization as an adult. Anyway, lots of studies have shown that children who experience trauma -- violence, sexual assault, an incarcerated parent, etc. -- have worse health outcomes as adults (For a variety of reasons). Sexual assault doesn't lead to UC, but sexual assault can certainly put someone on a path that eventually makes them at risk for a lot of negative health consequences that may eventually lead to UC.

https://www.cdc.gov/violenceprevention/acestudy/index.html
Left-sided colitis dx on 12/28/17, with concurrent onset of chronic hives & food allergies (wheat, peppers).

4.8g Lialda (1 month) Budesonide 9mg (3 weeks) Prednisone
Saccharomyces Boulardii 2x/day
40mg Zyrtec, 300mg Zantac & Singular for the hives
20mg citolopram for depression
500mg metaformin for PCOS

beatUC
Veteran Member


Date Joined Mar 2010
Total Posts : 1440
   Posted 3/12/2018 3:57 PM (GMT -6)   
"likely to admit to physical/sexual abuse is also more likely to admit to having ulcerative colitis" Man, that seems like stretch! We don't have to "admit" to UC, its a disease, you are diagnosed with it, it's not an opinion or something you would keep as your special secret. When you end up hospitalized with tubes coming out of you, I think the "admitting" you have UC is over. UC is a serious, sometimes life threatening disease. C'mom now attitudes like this are what prevents us all from being taken seriously and the research funding that follows...
Imuran
Asacol
Rowasa
prednisone as needed

Uniform Charlie
Veteran Member


Date Joined Jul 2015
Total Posts : 726
   Posted 3/12/2018 4:35 PM (GMT -6)   
Beat UC, your pulling one sentence out of context, then feigning outrage over it and saying this somehow leads to a lack of research funding is a bit more of a stretch than the original statement don't you think?

I don't live in Fantasyland, just somewhere that people tend not to talk about their bowel habits or their childhood abuses as a part of normal conversation. I'm not saying that people SHOULDN'T talk about UC, just that they tend not to.

Spring
Regular Member


Date Joined Jan 2017
Total Posts : 390
   Posted 3/12/2018 6:52 PM (GMT -6)   
I listened to several TED talks about childhood trauma and the connection to poor health later in life. One thing that was discussed is how trauma in children primes the fight or flight response to be stuck on. They said that it had the potential to alter the DNA if prolonged enough. Here is a link to one article that talks specifically about it.

https://www.genengnews.com/gen-news-highlights/childhood-trauma-can-alter-dna/81247708

ambling
Veteran Member


Date Joined Feb 2011
Total Posts : 760
   Posted 3/12/2018 9:06 PM (GMT -6)   
From the article:

"...we found no association between either type of abuse and Crohn's disease"

Seems very odd indeed.

Connor77
Veteran Member


Date Joined Jul 2016
Total Posts : 523
   Posted 3/12/2018 11:14 PM (GMT -6)   
Childhood abuse and PTSD can certainly shape your stress response, which we all know is related to UC.
DX left-sided UC 2015, 3 fulminant flares since then
Started FMT clinical trial Feb 2018
Dx w/mycobacterium avium paratuberculosis (MAP) Sept 2017
Stopped AMAT @ 6 weeks due to intolerance of meds
Others: Entyvio every 4 weeks, Low Dose Naltrexone 3mg at bedtime, natural ferments
Current status: lingering rectal bleeding, otherwise healthy

quincy
Elite Member


Date Joined May 2003
Total Posts : 30976
   Posted 3/13/2018 12:26 PM (GMT -6)   
Conner....Still separate issues....not connected or related as per the "study".
q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma); Effexor XR 75mg (depression); Rosuvastatin 10mg (cholesterol); Telemesartin 80mg / Amlodipine 5mg (BP)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care + Genuine Health Advanced Gut Health 15 billion @ bedtime)
~Metamucil capsules 6 @ 2x daily with meals; Vitamin D 4500 IU
~URSO 500mg @ 2x daily for Primary Biliary Cholangitis
"TREAT (FROM)BOTH ENDS" worth it !!

HJQuinn
Regular Member


Date Joined Jan 2018
Total Posts : 44
   Posted 3/13/2018 2:13 PM (GMT -6)   
....I think it's the years of repressing very strong emotions. Emotional pain and trauma do have a direct connection to UC. It makes sense that a percentage of those who suffered childhood abuse would be prone to UC or other autoimmune issues.


"A calm heart is the life of the fleshly organism." - Proverbs 14:30

notbob
Regular Member


Date Joined Jul 2016
Total Posts : 69
   Posted 3/13/2018 9:37 PM (GMT -6)   
Interesting stuff. I agree the study doesn't directly correlate, but I think it presents a reason for more study into stress response and autoimmune disease.
UC for 10 years, last two+ had the never ending flare from hell. Tried the usual meds, pills, steroids, biologics, diet, supplements and nothing worked. Had perm ileostomy Feb of 2017. Feel great!

imagardener2
Veteran Member


Date Joined Jan 2010
Total Posts : 5774
   Posted 3/14/2018 4:42 PM (GMT -6)   
Epigenetics can make genes "turn on" depending on external factors. Stressful life situations would be a factor. But what makes one child/adult get UC when none of their siblings do? They share similar genes and grow up in same stressful home.

And what about children who have UC at birth or have a very happy family and still get IBD?

I still believe my UC cause was a virus or bacterial invader, although stress could be a contributing factor.
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