Not quite the same. There are two main differences and a few notes to add in. Enzymes, including those of bacteria, operate best under ideal ph conditions which would be ideal by having food stuff introduced to both stomach acid, bile acids and allowing the intestinal tract to regulate the ph. The second is time. Average healthy digestion is 24 hours on the low end with bacteria being introduced relatively quickly. Time allows bacteria to degrade the fibers as well as the epithelial cells to absorb the necessary products. Another note to add in is how long the enema could be held in without expelling and creating a bacteria washout effect. These factors all would disturb the ideal conditions of scfa production. If the goal is butyrate, I would think butyrate supplements would be more efficient and come with the added bonus of sodium absorption if diarrhea is an issue. Butyrate enemas are a thing I believe. This is just my opinion though with the information that's already in my head so not the end all opinion.
Yes, good points and your analysis on butyrate and short chain fatty acids is consistent with what I have read. I have heard of very good results with butyrate enemas but when I tried the butyrate enema it didn't go well for me. Granted, I already had a lot of rectal bleeding at that time, but it seemed to worsen it. I wonder if buytrate enemas are only effective when there isn't active bleeding?
Diagnosed with pancolitis March 2012 - Tried all drugs - steroids, mesalamine, etc. Currently on Vedolizumab (new experimental gut specficic monoclonal antibody) Currently, my entire colon has healed except for rectum and recto sigmoid - these ares are the most stubborn for me - nothing seems to work there except for very high doses of steroids