Imuran metabolizes into 6mp within your body. Taking 6mp saves a step.
Cyclosporine is like prednisone, a temporary rescue medication.
1. Remicade/humira/simponi are all tnf-alpha blockers, very similar meds and prescribed based on patient/doctor preference.
2. Xeljanz is a jak-inhibitor. Completely different than 1, 3 or 4.
3. Entyvio is a madcam1-blocker. Completely different than 1, 2 or 4.
4. Stelera targets regulatory cytokines IL-12 and IL-23. Completely different than 1, 2 or 3.
Generally you want to try at least 2 different classes of biologics with different mechanisms of action before considering a surgery. So far you've tried only one class. As there's a point of diminishing returns after failing two classes. Can a third sometimes work? Yes it can happen, some here were rescued by a third but your chance of success drops considerably after failing a second.
Moderator Ulcerative Colitis
John, 40, UC Proctosigmoiditis
Rx: Remicade @5mgs/kg/6wks; daily 75mgs 6MP, 4.8g generic-Lialda, and rowasaYou cannot spell sUCks without UC.
Post Edited (iPoop) : 9/3/2018 4:12:03 PM (GMT-6)