Hot off the presses Sept 25, 2018. Touches on a few of the favorite themes, mentions diet, fmt, etc.
Abstract and link to full article (no-gate)
In the twenty ﬁrst century, the changing epidemiology of inﬂammatory bowel disease(IBD) globally with increasing disease incidence across many countries relates to thealtered gut microbiota, due to a combinatorial effect of environmental factors, humanimmune responses and genetics. IBD is a gastrointestinal disease associated with agut microbial dysbiosis, including an expansion of facultative anaerobic bacteria ofthe family Enterobacteriaceae. Advances in high-throughput sequencing enable us toentangle the gut microbiota in human health and IBD beyond the gut bacterial microbiota,expanding insights into the mycobiota, virobiota and helminthes. Caudovirales (viruses)and Basidiomycota,Ascomycota, and Candida albicans (fungi) are revealed to beincreased in IBD. The deconvolution of the gut microbiota in IBD lays the basis forunveiling the roles of these various gut microbiota components in IBD pathogenesisand being conductive to instructing on future IBD diagnosis and therapeutics. Here wecomprehensively elucidate the alterations in the gut microbiota in IBD, discuss the effectof diets in the gut microbiota in relation to IBD, and illustrate the potential of manipulationof gut microbiota for IBD therapeutics. The therapeutic strategy of antibiotics, prebiotics,probiotics and fecal microbiota transplantation will beneﬁt the effective application ofprecision microbiome manipulation in IBD.
(PDF) The Gut Microbiota in the Pathogenesis and Therapeutics of Inflammatory Bowel Disease. Available from: https://www.researchgate.net/publication/327859590_The_Gut_Microbiota_in_the_Pathogenesis_and_Therapeutics_of_Inflammatory_Bowel_Disease [accessed Oct 09 2018]./www.researchgate.net/publication/327859590_The_Gut_Microbiota_in_the_Pathogenesis_and_Therapeutics_of_Inflammatory_Bowel_Disease
Moderator Ulcerative Colitis
John, 40, UC Proctosigmoiditis
Rx: Remicade @5mgs/kg/6wks; daily 75mgs 6MP, 4.8g generic-Lialda, and rowasaYou never really appreciate what you've got until it's gone. Toilet paper is a good example.