I generally take Apriso in the AM hours. My GI wants me to take it as early as I have "light breakfast", and then take Pantoprzole around lunch time. So we are talking 5-6 hours apart.
And...I treat it from both ends
My GI says (and it makes logical sense to me) that even if we loose some potency of Apriso due to PPI neutralizing acid, we will still get it with enema later in the day.
Post Edited (totallyi2015) : 11/10/2018 1:16:32 PM (GMT-7)