ks1905, I think you are definitely right about the muscle atrophy in the sphincter, and the importance of kegel exercises in my situation. I am very surprised that I have never thought about these before (in my own context), and I have never read anything mentioning these before either. Doctors and surgeons haven't said anything too, which is not surprising.
Thanks for mentioning. Your caution makes sense biologically. I am curious, have you read anything about this before, or did you just thought about it now?
I am on pentasa, 6mp, and Cimzia, in addition to a strict diet and some supplements. I will replace Cimzia with Stelara as a next step, because Cimzia hasn't made a difference good enough to eradicate the inflammation, it only reduced it to a degree.
There was a former member here (Pluot) who was an undergrad and had surgery before she went to Medical School to become a GI. I had the same surgeon as Pluot and we went to the same GI practice. She was about
a year ahead of me in the surgery timeline.
She researched all of this a lot more than I did but I remember her mentioning a couple of times that 2-3 year mark was when you should really make a decision because of muscle atrophy.
Cimzia never really worked for me.
Stelara worked right away for me, like two days later. It is very fast acting. I had to discontinue Stelara for 8 months when I had to go for hip surgery. I was able to restart Stelara without any antibodies or side-effects. My GI recently ran a promtheus test on me to see if I had any Stelara antibodies and I didn't have any.
If you're going for a takedown then you'll probably have to discontinue your biological and 6-mp for the healing process. What are you going to do in the interim for your IBD symptoms? I was able to start and stop Stelara without any issues, I'm not sure that I could have done that with Cimzia or another anti-tnf biological. I used antibiotics to treat my pouchitis while I was recovering from hip surgery.
I'd encourage you to try Stelara sooner than later, waiting is not a good option. How long have you been on Cimzia?
DX'd with Severe Pancolitis June 2005
Previous Meds: 5ASAs, Predisone, 6-MP. Remicade, Humira, Simponi, Cimzia & Cyclosporine
3-step J-Pouch surgery: 2013 & 2014
Current Condition: Chronic Pouchitis -- Not as bad as I thought it would be
Current Meds: Stelara
Total Hip Replacement: 12/16 -- Thanks Prednisone!!!www.healingwell.com/community/default.aspx?f=38&m=3755226
Post Edited (ks1905) : 12/17/2018 2:09:18 PM (GMT-7)