Ive read the thread initially....but this time, only from last seen post. Therefore ass-uming the taper was pred. Apologies.
Could you explain why tapering xeljanz....because of the side effects? You have more patience than I would ever.
Were you tapering the rowasa because of side effects as well?
I get the comparison....
It’s not really a taper, per se. The Xeljanz dosing for UC is 10mg 2x/day for an induction period, after which you either stay at that dosing for maintenance, or you step down to 5mg 2x/day. It’s possible that I could curb/tolerate the side effects at the lower maintenance dose. Since it seems like the Xeljanz is helping the UC, I’m willing to hold on a little bit longer (limited by the weight I’m losing weekly) before stepping down if it gives me a better shot at maintaining on the lower dose.
I’m trying to step back the Rowasa because I have ridiculous cramping with the Xeljanz and I’m running to the bathroom shortly after using it (because I’m running to the bathroom pretty much constantly). Using the Rowasa makes me more aware of the cramping, and when I use it I end up taking longer to fall asleep, and I wake more frequently during the night. Since the blood has all but gone away, I was hoping I could taper back on the Rowasa in an attempt to get more sleep/experience less pain.
My typical UC flare “pain” is more of an intense, gripping discomfort. Since about
1 week into the Xeljanz that changed to stabbing cramps— and urgency no longer defined by rectal inflammation but by the cramping pain. Xeljanz feels just like the crappiest GI virus I’ve ever had.
Dx: 5/17/17; flaring since 3/2018
Rx: Lialda 1.2gx4, Uceris, Humira (fail), Xeljanz
Post Edited (Celeriac) : 12/30/2018 1:00:07 PM (GMT-7)