Quick backstory. I was diagnosed at 17 and I’m now 26. I’ve only had one 6 month period of remission in that time. I have severe pan colitis .
I have been on Uceris and Prednisone, which I now have a resistance to. They have ZERO impact on my condition other than systemic side effects.
I’m allergic to mesalamines. Saw no results with Imuran/6mp/mercaptopurine.
In December 2017, I was hospitalized, lost a severe amount of weight, colon was so inflammated that it was causing a blockage etc. I started Humira during that time and began to saw a little Relief but it was very short lived. Began flaring fairly quickly.
I then started Remicade. I am now going on my 5th infusion. I get them every 6 weeks and I’m at the “doubled” dose. I feel better almost immediately. I go from 10-15 BMs a day down to 1-2 BMs however it’s still always urgent, and diarrhea..
Unfortunately the infusion effects on last about
2-3 weeks and I begin flaring and waiting for my next dose.. My doctor says I’m at the max dosage of Remicade I can receive.. She opted to start me on Mercaptopurine again to see if they would work better together.
So my question is, when would you ditch the Remicade and start a new biologic? Is it normal for it to work, but only for a few weeks?
Is having diarrhea still even tho I feel mostly better normal?
Has anyone else experienced something similar ?
Post Edited (UC_girl) : 1/16/2019 9:53:43 AM (GMT-7)