Canasa Suppositories side effects?

Hello everyone!! Hope everyone’s having a great week so far.

I’m back seeking some advice. I’ve been on Canasa (mesalmine) suppositories for a little over 2 months now. They stopped my bleeding and mucus, and have firmed up my stools which is amazing.

What is bothering me now is (what I believe) to be a side effect from these suppositories. I take mine before bed, and obviously in the morning there is the inconvenience for the “expelling” of the waxy white liquid into the toilet. Gross, I know. However, I have been feeling like this waxiness has actually made it difficukt for me to hold in stool? Almost like it just slips right down to where I have to pass it l? I have been passing stool probably 3/4 times per day, but the stools are always formed (maybe on the thin side), normal in color, and low volume. It’s almost like I’m passing my usual amount of stool, just instead of 1/2 larger volume stools, I’m passing 3/4 smaller size ones, but with a slippery feeling that they just kind of shoot right out? (I know, again, gross)

This access in passing stools has aggravated my internal Hemmies a bit and, while manageable, is annoying. I was thinking of asking my doctor to see if I could try doing a supp once every other night, and then wean down to maybe one a week from there? I have noticed on the nights I’ve forgotten the supp I don’t have this issue.

Has anyone else had similar side effects with Canasa suppositories?? I don’t think I’m still flaring as I have no other symptoms.

Thank you!

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Age 22, diagnosed at age 8 - remission from age 9 to age 20. Have had one flare per year since. UC and internal hemorrhoids, so proctitis tends to be my main issue.

Current meds:
-Lialda (3 pills)
-VSL3
-Canasa Suppositories
-Tumeric Capsules
-Hydrocortisone cream (for internal hemmies)

Normal to expel some of the melted parts of the suppository if pushing any time when sitting on the toilet to urinate or when having gas.

q

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*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Oxeze/Airomir (asthma); Effexor XR 75mg (depression); Rosuvastatin 10mg (cholesterol); Telemesartin 80mg (BP)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care + Genuine Health Advanced Gut Health 50 billion @ bedtime)
~Metamucil capsules 6 @ 2x daily with meals; Vitamin D 4500 IU
~URSO 500mg @ 2x daily for Primary Biliary Cholangitis
~Sjogren's (secondary)...symtomatic treatment
"TREAT (FROM)BOTH ENDS" worth it !!

Thanks everyone - sometimes just hearing "normal" is all I need, but the rectal foam idea is one I hadn't considered. I might look into it!