It is interesting. The class of drug has had a big success in treating Multiple Sclerosis. See https://en.wikipedia.org/wiki/sphingosine-1-phosphate_receptor_modulator
I am not fully clear if this is a biologic. It seems small molecule, and seems synthesized, rather than grown in a living organism. Possibly just one more immuno-modulator drug.
The only similar drug on the market targets not only SP1 but also SP2 thru SP5. I see on the Wikipedia page that for MS, an SP1 only version failed Phase III trials.
The phase-II results summarized in the article do seem efficacious with low side effects.
11/08: ischemic colitis and scope perf colon. 12cm colon/ileocecal resected. IV antib:sepsis.
01/10: Dx: Mod. UC pancolitis
. Rx: Lialda 3x.
02/11: Major flare w/antib:sinus. Rx: 40mg Pred taper.
07/11: Histol remiss rt/trans; worse sigmoid. Rx: Rowasa & hydrocort
Curr: 1-2 soft-formed stool, no urgency: Lialda 2x, NO PRED, probiotics, Vit-D/C