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Vitamin D and colon stem cells

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Ulcerative Colitis
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Oligodar
Regular Member
Joined : Jul 2017
Posts : 242
Posted 7/18/2019 7:32 AM (GMT -6)
Vitamin D differentially regulates colon stem cells in patient‐derived normal and tumor organoids
https://febs.onlinelibrary.wiley.com/doi/abs/10.1111/febs.14998
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imagardener2
Veteran Member
Joined : Jan 2010
Posts : 5896
Posted 7/19/2019 7:37 PM (GMT -6)
Can you say what conclusions are or what they think are the results please.
I cannot read the paper, just the 1st paragraph. Plus even if I read it all am not a scientist to understand results.
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Oligodar
Regular Member
Joined : Jul 2017
Posts : 242
Posted 7/20/2019 12:26 AM (GMT -6)
I do not have access to full article and I am not a scientist neither.

Key message for me:

1. D3 works directly in our intestines, not only on systemic level.
2. In normal healthy tissue it inhibits cell proliferation
3. In tumor It behaves different way.

It is basic research. No practical conclusion can be taken from it. But there can be potential for developing anti cancer drugs in future.
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