Posted 7/25/2019 6:28 AM (GMT -7)
Welcome to the forum, but I am sorry to hear your daughter is flaring. My assessment is your daughter is having a severe flare with 6-7 bms a day, and is being very under-treated for her flare. She needs stronger medication dosages, and maybe even stronger meds to recover from her flare. I would press this with her pediatric gasteroenteroligist.
With 6-7 bms a day, rectal meds might be hard to retain for long, expected. A steroid would heal that area faster, and enable you to then go back to the safer mesalamine.
I know pediatric dosages of mesalamine are lower, especially for a 10-year old. For an adult it would be 4,800-mgs a day of oral mesalamine, and 4,000-mgs a day of rectal-route meds. You are saying an oral dosage of 1,250-mgs a day, and 1,000-mgs rectal-route which still seems pretty low even for a child. I would ask your pediatric gasteroenteroligist if that dosage could safely be increased for a child of her age and weight. I would ask her doctor about stronger medications, as she is still suffering. Might be time for an oral steroid to control things faster.