After battling the insurance company for months, I have been on Xeljanx since March. Started out on the 10mg x 2 daily starter dose. Seemed like it was working, but could have been the lingering benefit from Prednisone taper.
Dropped to 5mg x 2 daily and quickly started to slide downhill quickly. Blood/mucous/multiple BM.
Doc re-upped me to the 10mg x 2 dose mid June with no improvement since then for me.
Back on Prednisone 50 & 60mg not helping either with the Xeljanz. Very odd Prednisone is not helping either.
Important to note that the higher 10mg dose was just given a FDA black box warning due to high risk of blood clots and some docs are skipping the higher starter dose now. I'm taking a baby aspirin to mitigate clot risk (I know, contra to UC guidelines, but GI was OK with it.) I think I'll be discontinuing Xeljanz shortly, so I'm not overly concerned.
I wish you luck with your Xeljanz treatment!
This happened to me too!!! I was advised to go back up to 40mg Pred 7 weeks ago and it did nothing! Really unusual for me as usually it sorts me out fast. Hence why my doctor wrongly thought that my bleeding could be unrelated to the UC.