a year ago, I was casually discussing that I had UC with a friend. And he mentioned that his sister had Crohn's, and after a long and tough struggle, doctors found that it was Prozac (maybe Zoloft?) that was the key to helping her get better. I don't know specifics (e.g. whether it helped her into remission or maintained it or other meds she was on) but it was something I just now thought to investigate. I didn't think much about
And I just found this study done last year:
This is the longer article explaining its findings: https://www.medpagetoday.com/gastroenterology/inflammatoryboweldisease/77004
It looks like antidepressants can be quite beneficial for some patients. I don't want to summarize here as these studies are complicated but the moral of the story is that:
"In this nationwide study, antidepressant use was found to be beneficial on the disease course among patients with UC and CD, particularly in patients with no use of antidepressants before IBD onset."
"Kristensen and colleagues noted that in terms of potential pathways, antidepressants affect levels of pro-inflammatory cytokines such as interleukin and TNF, known to be involved in the pathogenesis of IBD. "Hence, decreased levels of pro-inflammatory cytokines may explain the observed favorable influence on the course of IBD," the team wrote, adding that antidepressants also positively affect brain-gut interaction."
I find it really validates what a lot of us here talk about
: the mind/gut connection. And, at least for me, I get very frustrated with doctors who rarely talk about
this psychological connection (and diet for that matter). Anyways, this study is super recent--just last year--so it's worth reading, if only for a different take.
Prozac, here I come?
36 yr old man
Diagnosed UC 2006
Currently: Lialda / Imuran / Inflectra
Post Edited (DavidEA) : 8/16/2019 11:14:07 PM (GMT-6)