Posted 8/20/2019 2:36 PM (GMT -6)
I received my pathology report back this afternoon, and I thought I'd post it while I wait for an appointment.
1. Polyp (2mm) in the sigmoid colon.
2. Scarring in the hepatic flexure.
3. Significant scarring in the ascending colon.
4. Polyp (2mm) in the descending colon.
5. Normal mucosa in the descending colon.
6. Normal mucosa in the sigmoid colon.
7. Edema in the sigmoid colon at 37cm.
8. Mass (8mm) in the sigmoid colon at 30cm.
A. Colon, sigmoid, polypectomy: Fragments of tubular adenoma.
B. Colon, hepatic flexure, biopsy: No prominent active colitis identified.
C. Colon, descending, polypectomy: Early hyperplastic changes.
D. Colon, descending, biopsy: No prominent active colitis identified.
E. Colon, sigmoid, biopsy: No prominent active colitis identified.
F. Colon, sigmoid (37cm), biopsy: Moderate active colitis (see microscopic).
G. Colon, sigmoid "mass" (30cm), biopsy: Consistent with small cell neuroendocrine carcinoma (see microscopic).
F. Sections show a moderate neutrophillic infiltrate of the lamina propria and epithelium. The lamina propria is expanded by prominent chronic inflammation, and the mucosal architecture is altered. These findings would be consistent with a moderate active colitis with evidence of chronicity. Correlation with clinical findings is recommended.
G. Sections show the presence of colonic mucosa, many showing an infiltrate of tendrils of small epithelial cells with only minimal associated cytoplasm and extensive crush artifact. This intercalates between bland epithelial elements. Immunohistochemical studies were performed and showed these lesional cells to be positive for CD56, chromogranin, TTF-1, synaptophysin and pancytokeratin (AE1/AE3), and negative for CD45. In addition, near ubiquitous staining for Ki -67 was noted (greater than 95%). These findings would support a diagnosis of small cell neuroendocrine carcinoma. A Immunohistochemical studies were performed at (lab) and interpreted at (doctor).