I intend to post this on the Microscopic Colitis support forum (URL Deleted) as well, but since Mutaflor is clinically proven to treat UC as well as all forms of colitis, I thought this could be of interest for UC sufferers, since it brings a new perspective (dosing) relative to existing clinical studies.
I’ve been having diarrhea about
7 times a day, as well as abdominal pain, for 2.5 months.
I had a colonoscopy 4 weeks ago, and since it showed ulceration and I had blood for 2 days before, my GI doctor thought I had UC, and put me on Uceris (actually generic budesonide ER) and mesalamine.
However, the biopsies later showed evidence of lymphocytic colitis. Perhaps I have some kind of hybrid form.
The blood never came back, and the cramps, after a flare, subsided.
However, the diarrhea persisted.
After two weeks without amelioration, I started taking Mutaflor instead of a regular probiotic, based on the abundance of successful clinical studies.
It stopped the diarrhea cold after the first pill, and I had only one BM a day, much firmier.
However, even after doubling the dose to 2/day after 4 days as indicated, the diarrhea came back after 3 days.
After a few days, I decided to double the dose again, 4/day.
The diarrhea stopped again, and I got perfectly formed stools for the first time in months.
3 days later, the diarrhea came back again. I upped the dose to 5/day, and it went away again.
Now I’m taking 4 a day, but one before each meal, ready to up the dose if needed.
The maximum recommended sustained dose is 4/day, but for chronic constipation the initial recommended dose is 6/day for 3 days, so this should be safe.
All the studies I’ve seen used only 2 pills a day, but in fact I found the effect to be dose-dependent, as shown by this very well-made study: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc1064918
This shows the profound immuno-regulating and anti-inflammation effects of the bacteria, but most importantly, demonstrates the dose-dependent aspect.
So if you’ve tried Mutaflor before and it didn’t work, consider upping the dose until it does, and consider taking it before each meal.
You can find it online for about
$1.33 a pill in the US.
I have no commercial interest in Mutaflor or any other product, I’m just sharing my experience (and this study) in hope it could help other people like it did for me.
(I removed the link to another forum system in your
Post Edited By Moderator (iPoop) : 8/29/2019 7:19:54 AM (GMT-6)