Here's an article about
the meta-analysis regarding NSAIDs: https://www.medpagetoday.com/gastroenterology/inflammatoryboweldisease/72655
"A systematic review and meta-analysis has found no consistent overall association between worsening inflammatory bowel disease (IBD) and acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs) or cyclooxygenase 2 (COX-2) inhibitors.
The findings, published in Alimentary Pharmacology and Therapeutics, run contrary to prevailing thought that NSAIDs may exacerbate Crohn's disease (CD) and ulcerative colitis (UC). For example, the American College of Gastroenterology's guidelines for management of IBD recognize NSAIDs as potential triggers for disease exacerbation.
'Contrary to the general belief, we did not find a consistent association between use of NSAIDs and risk of IBD exacerbations,' Hamed Khalili, MD, MPH, of Massachusetts General Hospital in Boston, told MedPage Today. 'This was surprising to us as generally clinicians advise against use of NSAIDs in patients with established IBD. But we caution against any changes in current practice as significantly more work is required to examine the safety of acetaminophen and NSAIDs in patients with CD and UC.'"
Basically, they need to do more studies. And they found Tylenol exacerbated symptoms in some people. I think that was only in Crohn's patients though; I can't remember.
And here's one study I had read about
this same topic: https://www.ncbi.nlm.nih.gov/pubmed/26485106
CONCLUSIONS: Regular (≥5 times/mo) NSAID and acetaminophen use were associated with active CD, but not UC. Less frequent NSAID use was not associated with active CD or UC. These findings indicate that regular NSAID use may increase CD activity, or that NSAID use may be a marker of a less robust remission; thus reflecting subclinical disease activity.
35 years old; diagnosed UC March 2007 (prob. pancolitis; couldn't get scope all the way thru).
9-29-16: chronic and active proctosigmoiditis (infectious cause). Battled reoccuring campylobacter & c diff. Oct-Dec 2016. Remission since Dec. 25, 2016 until I started smoking again May 2018 after 9 yrs quit. Maintenance: Delzicol, 6, 2xday; Rowasa nightly. Started Remicade 7/25/19.
Post Edited (Sara14) : 9/17/2019 5:32:46 PM (GMT-6)