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Safe NSAID?

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Ulcerative Colitis
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CCinPA
Veteran Member
Joined : Dec 2014
Posts : 1593
Posted 11/18/2019 5:11 PM (GMT -6)
Is there any safe anti inflammatory med that we can take? I know we aren't supposed to take ibuprofen, but I need something to take for knee pain (osteoarthritis). I take arthritis strength tylenol that helps a little with the pain, but does nothing for the inflammation which is causing the pain. (I did take ibuprofen for several days this past week and today had a lot of blood so stopped taking it)
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Uniform Charlie
Veteran Member
Joined : Jul 2015
Posts : 1096
Posted 11/18/2019 5:25 PM (GMT -6)
The data on ibuprofen is actually mixed. I take it when I'm sick or injured and have never had a problem. CBD is an option.
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iPoop
Forum Moderator
Joined : Aug 2012
Posts : 16212
Posted 11/18/2019 5:31 PM (GMT -6)
Some of us take a rare NSAID when dealing with menstrual cramps, joint aches and the like (sometimes okay for infrequent use but not completely risk-free).

If you find you need them more regular than you'd like then asking for a prescription cox-2 inhibitor like celebrex is recommended and safer alternative to NSAIDs.

NSAIDs block both cox-1 and cox-2.
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Sara14
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Joined : Mar 2007
Posts : 6235
Posted 11/18/2019 6:09 PM (GMT -6)
Do you see a specialist for the osteoarthritis? If so, I would explain the situation and ask them if they have any suggestions. I'm lucky in that I can take NSAIDs without any issues. I take Aleve for headaches (about 2-3 times per month on average). Is your knee pain something you deal with daily?
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CCinPA
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Joined : Dec 2014
Posts : 1593
Posted 11/18/2019 7:31 PM (GMT -6)
Up until a couple weeks ago it would just be stiff & ache a little after sitting for a while. Pain would go away after moving around. I didn't give it much thought. Then the weather changed and got colder and it started hurting a LOT. Last Monday it was so bad I went to OSS Urgent care after work. They took an x-tray and gave me a shot of steroids in the knee, but I'm still in a lot of pain. I haven't been seeing anyone, but have an appt for next Monday to see a specialist. I think I need physical therapy. Did that a couple years ago and it made a world of difference.

I was taking ibuprofen a couple times a day for about a week. I probably would have been ok if it wasn't so much.
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CCinPA
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Joined : Dec 2014
Posts : 1593
Posted 11/18/2019 7:32 PM (GMT -6)
Thanks for the info, John. Will ask about celebrex
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deltaforce
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Joined : Jun 2010
Posts : 2373
Posted 11/19/2019 2:09 PM (GMT -6)

CCinPA said...
Thanks for the info, John. Will ask about celebrex


My GI suggests staying away from Celebrex. In her experience, it isn't much better than Ibuprofen.

looked at Relafen (Nabumetone)? I have been using it for 6+years now without any problem. 1.5gm is equivalent to 200mg of Ibuprofen. Its a pro-drug so it needs to take more in amount and takes a while to kick in.
Also, search my older comments on it.
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Sara14
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Posted 11/19/2019 2:58 PM (GMT -6)
Let us know what the specialist recommends.
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CCinPA
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Joined : Dec 2014
Posts : 1593
Posted 11/19/2019 7:33 PM (GMT -6)
delta -- do you take relafen daily or as needed?
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straydog
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Joined : Feb 2003
Posts : 18366
Posted 11/19/2019 8:52 PM (GMT -6)
CcinPA, here is something else to consider instead of trying oral NSAIDS. I use an arthritis medication called Voltaren topical gel. I have never had a problem since it's a different delivery method. It is only available by script. I have a long history of knee problems with many scopes for different issues with my knees. They always try to clean things up some, but they can only do so much.

You can go to Drugs.com & look it up, same with Relafen.
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quincy
Elite Member
Joined : May 2003
Posts : 32636
Posted 11/19/2019 9:03 PM (GMT -6)
I've used Celebrex for over a year...no issues.

I'm now on LDN at 3mg and will be increasing to 4.5 next month....I'm definitely able to cut back on the Celebrex.

q
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geezernow
Regular Member
Joined : Nov 2017
Posts : 234
Posted 11/20/2019 3:16 AM (GMT -6)
CC...I know most people scoff at this, but I have had GREAT relief from minor arthritis pain, by drinking ginger root tea. Ginger root is available at most grocery stores, is easy to slice into thin pieces and all you need to do is boil it, let it seep, strain it, and add your favorite sweetener. I use about an inch of ginger root. Drink a cup every day and after a few days, you should find relief. Worth a try. You should check with your doctor first, just to be safe. Good luck.
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deltaforce
Veteran Member
Joined : Jun 2010
Posts : 2373
Posted 11/20/2019 6:28 AM (GMT -6)

CCinPA said...
delta -- do you take relafen daily or as needed?


In the past (when I started taking it in 2013), I needed 4 tablets daily i.e. 1.5g-x-1.5g to survive (could not function with headache) but after 2015, I have been taking as needed. Lately, my need has reduced significantly so nowadays I take like once a week or so.
I also take alcoholic extract of Turmeric and Boswellia capsules. They definitely help to keep use of Relafen in check.
Ginger root's idea is good too. I add grated ginger in turmeric-alcohol mixture while soaking process.

straydog said...
I use an arthritis medication called Voltaren topical gel. I have never had a problem since it's a different delivery method. It is only available by script..


Voltaren contains Diclofenac (Na or K salt). It is pretty much the same as Ibuprofen in terms of the side effect profile. I have used it. Just application on the forehead would lead me to the flare.

Everyone's tolerance is different. So unless you try you would not know. My headaches were so bad since Dx (2008) that I HAD to take Advil before going to work or I would not be able to function so I (ab)used Advil a lot between 2008-2013, just to be able to function. That led to the point that if I use any classical NSAID, I would end up pooping blood. Then my PCP suggested Relafen. While the effect is Relafen was never as good as classical NSAID, it helps me function.

Try under physician's supervision so you know what works with you and what doesn't.
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straydog
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Posts : 18366
Posted 11/20/2019 7:16 AM (GMT -6)
DeltaForce, I have never heard of anyone using Voltaren gel for headaches. I have used it for years without any issues. I use a lot of OTC analgesics, including the patches that has some lidocaine in them. When those stop working I use the Voltaren.

I had asked about Relafen early on, but if a person has any heart issues it's off the list.

Regardless, CCinPA has lots of options & hopefully will find something that works.
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deltaforce
Veteran Member
Joined : Jun 2010
Posts : 2373
Posted 11/20/2019 9:09 AM (GMT -6)

straydog said...
DeltaForce, I have never heard of anyone using Voltaren gel for headaches. I have used it for years without any issues. I use a lot of OTC analgesics, including the patches that has some lidocaine in them. When those stop working I use the Voltaren.

I had asked about Relafen early on, but if a person has any heart issues it's off the list.

.


My headache came with a stiff neck and my neurologist gave me a sample to try on the stiff neck.
Good to know that Relafen is not recommended for patients with cardiac issues, do you know why?
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tiredofallthispoop
Regular Member
Joined : Jan 2017
Posts : 218
Posted 11/20/2019 9:28 AM (GMT -6)
I have been using Curio Wellness Lemon Honey Chews which have CBD and THC at a 5:1 ratio. I usually have half of one at night before bed and if I am especially sore I might have 1/4 during the day. I find I am sleeping a lot better and wake up with little to no pain.
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Bull101
Veteran Member
Joined : Feb 2015
Posts : 653
Posted 11/21/2019 6:52 AM (GMT -6)

straydog said...
DeltaForce, I have never heard of anyone using Voltaren gel for headaches. I have used it for years without any issues. I use a lot of OTC analgesics, including the patches that has some lidocaine in them. When those stop working I use the Voltaren.

I had asked about Relafen early on, but if a person has any heart issues it's off the list.

Regardless, CCinPA has lots of options & hopefully will find something that works.

In Germany you don't need a script for Voltaren and my mom brought some back. I use it for extreme muscle soreness and stiffness, it's incredible.
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CCinPA
Veteran Member
Joined : Dec 2014
Posts : 1593
Posted 11/21/2019 11:41 AM (GMT -6)
Thanks for the suggestions everyone. I see the specialist on Monday. Right now my preference would be to try the topical first.

I'll be getting some ginger root to try for sure since I like ginger anyway smile
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MarkWithIBD
Regular Member
Joined : Jun 2018
Posts : 442
Posted 11/21/2019 12:35 PM (GMT -6)
Sorry to veer off topic slightly, but can anyone educate me on the science of precisely why NSAIDS are bad for us?
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tiredofallthispoop
Regular Member
Joined : Jan 2017
Posts : 218
Posted 11/21/2019 12:58 PM (GMT -6)
By blocking the Cox-1 enzyme and disrupting the production of prostaglandins. But I assume it does not affect everyone equally. I bleed just from taking fish oil. Others may never bleed. Maybe good to experiment?
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Sara14
Veteran Member
Joined : Mar 2007
Posts : 6235
Posted 11/21/2019 1:31 PM (GMT -6)
Mark: The science is nowhere near conclusive that they are bad for us.
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iPoop
Forum Moderator
Joined : Aug 2012
Posts : 16212
Posted 11/21/2019 2:48 PM (GMT -6)
Correct. The science isn't conclusive that NSAIDs are absolutely bad for us. It's a bit mixed, some studies say bad, other studies say inconclusive and they could not reproduce that it's bad for us. Current clinical recommendation is we should not take NSAIDs. I always add a BUT if you need to take them on rare occasion it isn't going to be end you. Just would not take NSAIDs regularly as there is some inherent risk in it.
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CCinPA
Veteran Member
Joined : Dec 2014
Posts : 1593
Posted 11/21/2019 5:30 PM (GMT -6)
I feel like such a wimp. I actually took some prednisone tonight because I have to get the inflammation down and I know that should work pretty quickly ~fingers crossed~ The pain is getting rather intense and the knee is swollen. I will see what the doc says Monday, but I am wondering if maybe this is bursitis rather than the arthritis.
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CCinPA
Veteran Member
Joined : Dec 2014
Posts : 1593
Posted 11/25/2019 6:46 PM (GMT -6)
Doc said mild to moderate OA (feels pretty darned bad -- can't imagine what severe would feel like!). I got a script for Voltaren gel and just put some on. Probably my imagination but seems like the pain has already decreased a bit. On Monday I will go for a PT evaluation and then start PT. He also recommended that I get Euflexxa (hyaluronic acid) injections in my knee since I just had a cortisone shot 2 weeks ago and he wouldn't do another one of those for 3 months. Waiting for insurance to approve the shots. It's a series of 3 shots given a week apart. Really cringing about the shots, but looking forward to getting some real relief from the pain

I also started drinking ginger root tea on Saturday. Can't say that I notice that it's doing anything. I made a whole pitcher full of the tea and fiddled with adding lime and honey until I got it tasting fairly good. When I read about the tea it sounds like it's good for many things so I'll drink all of it even if it isn't doing anything for my knee.

Stopped the pred today. 40 mg helped, but as I dropped the pain increased. I absolutely don't want to stay on prednisone so hopefully all the other stuff I am doing will get me through until I can get the shots and physical therapy.

It's hell getting old lol
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Sara14
Veteran Member
Joined : Mar 2007
Posts : 6235
Posted 11/25/2019 6:54 PM (GMT -6)
Sounds like you got a good game plan from your doctor. I hope it helps!
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