Open main menu ☰
HealingWell
Search Close Search
Health Conditions
Allergies Alzheimer's Disease Anxiety & Panic Disorders Arthritis Breast Cancer Chronic Illness Crohn's Disease Depression Diabetes
Fibromyalgia GERD & Acid Reflux Irritable Bowel Syndrome Lupus Lyme Disease Migraine Headache Multiple Sclerosis Prostate Cancer Ulcerative Colitis

View Conditions A to Z »
Support Forums
Anxiety & Panic Disorders Bipolar Disorder Breast Cancer Chronic Pain Crohn's Disease Depression Diabetes Fibromyalgia GERD & Acid Reflux
Hepatitis Irritable Bowel Syndrome Lupus Lyme Disease Multiple Sclerosis Ostomies Prostate Cancer Rheumatoid Arthritis Ulcerative Colitis

View Forums A to Z »
Log In
Join Us
Close main menu ×
  • Home
  • Health Conditions
    • All Conditions
    • Allergies
    • Alzheimer's Disease
    • Anxiety & Panic Disorders
    • Arthritis
    • Breast Cancer
    • Chronic Illness
    • Crohn's Disease
    • Depression
    • Diabetes
    • Fibromyalgia
    • GERD & Acid Reflux
    • Irritable Bowel Syndrome
    • Lupus
    • Lyme Disease
    • Migraine Headache
    • Multiple Sclerosis
    • Prostate Cancer
    • Ulcerative Colitis
  • Support Forums
    • All Forums
    • Anxiety & Panic Disorders
    • Bipolar Disorder
    • Breast Cancer
    • Chronic Pain
    • Crohn's Disease
    • Depression
    • Diabetes
    • Fibromyalgia
    • GERD & Acid Reflux
    • Hepatitis
    • Irritable Bowel Syndrome
    • Lupus
    • Lyme Disease
    • Multiple Sclerosis
    • Ostomies
    • Prostate Cancer
    • Rheumatoid Arthritis
    • Ulcerative Colitis
  • Log In
  • Join Us
Join Us
☰
Forum Home| Forum Rules| Moderators| Active Topics| Help| Log In

Biopsy results-don’t understand

Support Forums
>
Ulcerative Colitis
✚ New Topic ✚ Reply
❬ ❬ Previous Thread |Next Thread ❭ ❭
profile picture
chrissy72
Regular Member
Joined : Apr 2011
Posts : 221
Posted 11/25/2019 4:00 PM (GMT -7)
Was diagnosed with proctitis 8 years ago. Mostly been in remission.

Biopsy of cecum and ascending colon showed “findings consistent with quiescent phase of a chronic inflammatory response”. Rectal biopsy showed proctitis is not active right now.

Stupid patient portal through doctors office was how I got the results. The doctors note says continue meds and they recommend a follow up appt in 3 months or so. I don’t understand any of this. Does this mean I went from proctitis to pancolitis? If so, how come I didn’t have any symptoms outside of one day of diarrhea. Also, how did it just heal on its own? I’m only on Canasa suppositories. So if it went all the way up my colon wouldn’t they want me on oral medicines too and why wait for 3 months or more for a follow up?

Yes, I asked some follow up questions on their patient portal. Probably take a couple more days for them to respond. I’m so frustrated.
profile picture
Sara14
Veteran Member
Joined : Mar 2007
Posts : 6235
Posted 11/25/2019 4:10 PM (GMT -7)
It sounds like it means you're in remission. Quiescent means not active. I don't see why they would add any meds if you are in remission and not having any symptoms. I would have the same question as you, but I wouldn't worry too much about it.
profile picture
iPoop
Forum Moderator
Joined : Aug 2012
Posts : 16177
Posted 11/26/2019 7:09 AM (GMT -7)
Congrats on being in a remission (quiescent phase of a chronic inflammatory response)!

There are a few variants of UC that present in only the rectum and Cecum/Ascending colon. So, no, it is not a pancolitis now and it is not a crohn's disease (due to a skip lesion).

Inflammation within the cecum at the junction of the appendix opening: "Appendiceal orifice inflammation (AOI) is a common ‘skip lesion’ in patients with ulcerative colitis (UC)." https://www.ncbi.nlm.nih.gov/pmc/articles/pmc4071881/

The “cecal patch” in patients with ulcerative colitis
UC is a disease that classically begins just inside the anorectum and extends proximally (continuously) for a variable distance in a circumferential and uniform fashion, without “skip” areas. There are 2 types of segmental inflammatory change, however, that may be seen in patients with UC, and that may lead to confusion with Crohn's disease: backwash ileitis and the cecal patch; neither affects the course of the colitis.

An isolated cecal patch of inflammation, as in the present case, is present in many patients with left-sided UC or proctitis/proctosigmoiditis. We have learned that cecal inflammation may be part of normal cecal health, and that the cecum has a higher percentage of eosinophils, Paneth cells, and laminar propria inflammation than do other areas of the colon. The important lesson: don't diagnose Crohn's disease just because you see a patch of cecal inflammation in a patient with distal colitis. Pythagoras believed he could judge the height of Hercules from the length of his foot (ex pede Herculem), and from this it was extrapolated that from a sample one can judge the whole. This adage certainly is not evidence-based, and should not be used to rationalize judgment of the nature of colitis from the presence of a cecal patch. https://www.giejournal.org/article/s0016-5107(08)01639-8/abstract
profile picture
chrissy72
Regular Member
Joined : Apr 2011
Posts : 221
Posted 11/26/2019 9:09 AM (GMT -7)

iPoop said...
Congrats on being in a remission (quiescent phase of a chronic inflammatory response)!

There are a few variants of UC that present in only the rectum and Cecum/Ascending colon. So, no, it is not a pancolitis now and it is not a crohn's disease (due to a skip lesion).

Inflammation within the cecum at the junction of the appendix opening: "Appendiceal orifice inflammation (AOI) is a common ‘skip lesion’ in patients with ulcerative colitis (UC)." https://www.ncbi.nlm.nih.gov/pmc/articles/pmc4071881/

The “cecal patch” in patients with ulcerative colitis
UC is a disease that classically begins just inside the anorectum and extends proximally (continuously) for a variable distance in a circumferential and uniform fashion, without “skip” areas. There are 2 types of segmental inflammatory change, however, that may be seen in patients with UC, and that may lead to confusion with Crohn's disease: backwash ileitis and the cecal patch; neither affects the course of the colitis.

An isolated cecal patch of inflammation, as in the present case, is present in many patients with left-sided UC or proctitis/proctosigmoiditis. We have learned that cecal inflammation may be part of normal cecal health, and that the cecum has a higher percentage of eosinophils, Paneth cells, and laminar propria inflammation than do other areas of the colon. The important lesson: don't diagnose Crohn's disease just because you see a patch of cecal inflammation in a patient with distal colitis. Pythagoras believed he could judge the height of Hercules from the length of his foot (ex pede Herculem), and from this it was extrapolated that from a sample one can judge the whole. This adage certainly is not evidence-based, and should not be used to rationalize judgment of the nature of colitis from the presence of a cecal patch. https://www.giejournal.org/article/s0016-5107(08)01639-8/abstract

Thanks for your response. This whole thing has been confusing. The nurse from the GI office said doctor said I’m in remission but the biopsy results don’t correlate with what he saw during colonoscopy. He didn’t see any inflammation during colonoscopy and believed the abnormal vascularities were residual from the prep. I have a follow up appt on Dec 16th. The only med I’m on and still take is the Canasa suppositories. I had mild symptoms different from my proctitis to this for a week and a half. Just had two bouts of diarrhea for one day. No urgency, mucous or blood. I wonder if it went away on its own, without medication because I doubled up on my Visbiome probiotics.

Even though this is in remission wouldn’t I have to take some type of oral medication? The doctors office said no.
✚ New Topic ✚ Reply




HealingWell

About Us  |   Advertise  |   Subscribe  |   Privacy & Disclaimer
Connect With Us
FacebookFacebook TwitterTwitter PinterestPinterest LinkedInLinkedIn
© 1997-2021 HealingWell.com LLC All Rights Reserved. Our website is for informational purposes only. HealingWell.com LLC does not provide medical advice, diagnosis, or treatment.