An interesting read.
Impact of Historic Migrations and Evolutionary Processes on Human Immunityhttps://www.cell.com/trends/immunology/fulltext/s1471-4906(19)30210-8
Human evolution has been constantly influenced by pathogens; therefore, a great number of human genes linked to immune functions and immunity-related disorders have evolved along with humans.
Genetic variants that have been under evolutionary pressure can contribute to explaining the differences in the susceptibility to diseases observed across different populations.
The ancestry of individuals from different populations across the globe greatly influences their possibility of developing certain autoimmune diseases and inflammatory disorders.