Posted 12/6/2019 11:08 AM (GMT -7)
What you describe sounds like a case of disease progression in extent and severity, that permantently necessitates the usage of much stronger meds and dosages. You cannot get below 10-mgs of pred, means you need more to get by without pred. I would max out the anti-inflammatories, and if that does not work then go on to your choice of either Imuran/6MP or remicde/humira.
Max dosage of Balsalazide Disodium is 6,750mgs. That's a daily 9 pills (each being 750-mgs). And you should take one mesalamine enema a day (usually 4,000-mgs). Give that a 3 or so weeks to work. If you cannot get off of pred then talk about the other aforementioned meds. I do not think switching from Balsalazide Disodium to another mesalamine like lialda/pentasa/asacol would make much, if any difference. The differences among them are so minor, it is really a pipe-dream kinda hope.
"Could the Uceris cause the symptoms to be worse? My first dose was last Thursday(need more time?)"
Uceris will NOT make you worse. You should have a response in 2-weeks or less for Uceris.