Whereas supplements aren't regulated or studied, so these risks are totally unknown and cannot easily be quantified.
Supplements may not be regulated but any company that markets a problematic supplement will not remain in business for long. I myself check out purity and potency of the supplements I take thru ConsumerLab.com
It isn't fair to say that supplements aren't studied. There are dozens of studies published in PubMed.gov proving the efficacy of supplements. Even Big Pharma admits that the meds available today cannot cure IBD, they can only manage symptoms and help dampen inflammation.
But as long as I can maintain remission thru diet and supplements with little or no side effects, then why should I look for expensive meds that may have toxic side effects?
A very small sample of effective supplements:
http://www.ncbi.nlm.nih.gov/pubmed/25830661The most important clinical trials conducted so far refer to the use of mastic gum, tormentil extracts, wormwood herb, aloe vera, triticum aestivum, germinated barley foodstuff, and boswellia serrata.
In ulcerative colitis, aloe vera gel, triticum aestivum, andrographis paniculata extract and topical Xilei-san were superior to placebo in inducing remission or clinical response,
and curcumin was superior to placebo in maintaining remission; boswellia serrata gum resin and plantago ovata seeds were as effective as mesalazine.
In Crohn's disease, mastic gum, Artemisia absinthium, and Tripterygium wilfordii were superior to placebo in inducing remission and preventing clinical postoperative recurrence, respectively. Herbal therapies exert their therapeutic benefit by different mechanisms including immune regulation, antioxidant activity, inhibition of leukotriene B4 and nuclear factor-kappa B, and antiplatelet activity. http://www.ncbi.nlm.nih.gov/pubmed/1312317CONCLUSIONS: Four months of diet supplementation with fish oil in patients with inflammatory bowel disease resulted in reductions in rectal dialysate leukotriene B4 levels, improvements in histologic findings, and weight gain
Conclusions: Addition of curcumin to mesalamine therapy was superior to the combination of placebo and mesalamine in inducing clinical and endoscopic remission in patients with mild-to-moderate active UC, producing no apparent adverse effects.
Zinc deficiency is common in patients with Crohn's disease (CD), especially in those with skin lesions and growth retardation... Zinc deficiency may play a role in the formation and clinical course of fistulas.
Zinc carnosine, a health food supplement that stabilises small bowel integrity and stimulates gut repair processes