So what did he say you are supposed to do then? Sounds like a catch-22.
Yes, it is a very delicate situation. This is the first flare (in the 18 years I've had U.C.) that didn't respond completely to prednisone, so we were looking at biologics. The Valley Fever was found when they were doing the routine pre-biologics testing, which basically rules out biologics at this point.
While I was waiting to get in to see the infectious disease doc, my U.C. went into complete remission with just the pred (after about
35 days @ 40 mg). He put me on fluconozole (anti-fungal) with the instructions to slow taper pred. The fluconozole will stop the VF from reproducing, and if I can get the pred down below 20, my body will start to kill the existing VF in my lungs. They will recheck for VF in 3 months.
I'm really not sure what would have happened if the pred didn't get me into remission.,
I asked them about
Vedolizumab since it is gut specific, but it was like I was speaking Greek or something, just got a blank stare. He did mention the TNF blockers are the worst when it comes to VF because that is the exact way your body kills off the infection.