Posted 1/16/2020 9:07 AM (GMT -6)
Mezavant/lialda tablets are supposed to disintegrate and all you normally see are orange/red flakes in your stool. I would occasionally see a dud-pill in my stool, maybe once a month and that's no worries at all. If you are regularly seeing mezavant pills in your stool then the medication is not releasing, and it is not healing you. I would call your gasteroenteroligist and tell him/her of this problem. Usually the fix is to switch us to another mesalamine/5-ASA, perhaps Pentasa, Asacol, Apriso, etc.
The pills all have a PH-delayed-release coating, and a whole pill in your stool means that coating never dissolved and never released its med. Different brand mesalamines have different coatings, another brand might have a coating that does dissolve correctly for you. Each brand has a different target PH, different dissolve time on the coating, etc etc.