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Salafalk enemas

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Ulcerative Colitis
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jess*
Regular Member
Joined : Jan 2008
Posts : 78
Posted 1/28/2020 2:56 PM (GMT -7)
I have just begun 2 salafalk enemas daily plus oral salafalk. I am worried this may be hard on my liver, does anyone know if the enemas actually get absorbed through the body or it just stays entirely in the rectum?
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quincy
Elite Member
Joined : May 2003
Posts : 32560
Posted 1/28/2020 2:59 PM (GMT -7)
Do you have liver issues already? It's a topical as is the oral. Low absorption.

q
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jess*
Regular Member
Joined : Jan 2008
Posts : 78
Posted 1/28/2020 3:02 PM (GMT -7)
No I don't have liver issues but I worry about all the salafalk I take when I'm flaring. I am definitely a worrier😟
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quincy
Elite Member
Joined : May 2003
Posts : 32560
Posted 1/28/2020 3:05 PM (GMT -7)
It's not metabolised through the liver, but it does do a second pass once in the bloodstream (which is a very small amount).

Does your doc do regular liver and kidney blood testing?
q
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jess*
Regular Member
Joined : Jan 2008
Posts : 78
Posted 1/28/2020 4:28 PM (GMT -7)
Once a year, you as well?
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C_G_K
Veteran Member
Joined : Dec 2006
Posts : 1414
Posted 1/28/2020 5:54 PM (GMT -7)
Just get a complete metabolic panel (blood test) done periodically if you're worried about it.
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quincy
Elite Member
Joined : May 2003
Posts : 32560
Posted 1/28/2020 10:26 PM (GMT -7)
I have mine done 2x yearly by my hepatologist.
q
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iPoop
Forum Moderator
Joined : Aug 2012
Posts : 16194
Posted 1/29/2020 7:29 AM (GMT -7)
You'll be fine. Mesalamine is a 90% topical med, the rest we pee out (can darken your pee). So, only a small amount goes through the kidneys.
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