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Pentasa suppository

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Ulcerative Colitis
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Posted 1/5/2021 8:48 AM (GMT -7)
What is the highest dose I can take daily? I feel a lot of pain and burning, it is driving me crazy.Any suggestion would be appreciate, thanks



I am taking 1g 2xdaily Pentasa and 1 x daily entocort suppository.

Stelara every 8 weeks since September
Posted 1/5/2021 9:59 AM (GMT -7)
Krica, from what I read with Pentasa 4g is the max per day. I would call the dr's office & leave a message for him to return your call to discuss this. You can also ask him about the Entocort. I had a terrible time with proctitis & Proctocort was my saving grace for the mucus, diarrhea & burning, however my problems were on the bottom end of things. Maybe ask him about enemas? If you are having what I call acid poop that burns your outer skin too, get some calmoseptin it works, available OTC. I always keep it on hand. The acid poop is painful.

Take care.
Posted 1/5/2021 11:13 PM (GMT -7)
Hi, thanks for your advise, the burning is inside botton end, I have ulcers in my rectum, I have being using entocort and 2 g pentasa, but it is not helping at all😔
Posted 1/6/2021 12:04 AM (GMT -7)
Are you meaning right inside the anus? Could be a fissure or hemorrhoid.
q
Posted 1/6/2021 6:56 AM (GMT -7)
The highest dose of mesalamine I've been prescribed by my gasteroenterologist is 4.8 grams orally, and two 4.0 gram enemas daily. That's a grand total of 12.8 grams mesalamine daily. It's very difficult to overdose on mesalamine at UC doses. The usual max prescribed is 4.8 grams oral and 4.0 retention enema for a grand total of 8.8 grams daily.

Certainly, there's a point where the effectiveness of mesalamine is questioned and moving on to stronger meds (azathiopurine and/or remicade) is therefore warranted.
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