Posted 1/23/2021 6:00 PM (GMT -6)
I am also considering Entyvio right now and GI ordered it. I wish I could be on mesalamine because it's definitely the safest drug for UC, but unfortunately developed hypersensitivity to it. In terms of biologics, my understanding is that Entyvio is gut specific so it doesn't suppress the entire immune system like other biologics. Theoretically it would have a better safety profile. Risk of cancer that I saw was 0.4 compared to 0.3 placebo. Risk of infections is higher though with biologics overall.
Here is an article on infection risk w/ Entyvio: https://academic.oup.com/ibdjournal/article/24/11/2431/4993052