Posted 1/25/2021 12:07 PM (GMT -6)
Long story short: Last May my mouth erupted in sores and lips swelled up for about a week. Concurrently, I developed all different types of sores on my hands: some in the form of blisters, some tear-dropped shaped, some with bullseye targets. Prednisone and Valtrex has largely kept this under control. I was tested for everything under the sun (biopsies, scrapes, labs, also tested for Crohn's and I don't have it), including very rare tests for very rare skin disorders, over the last seven months and everything came back negative. They've settled on erythema multiforme via an entire dermatology department who was trying to figure this out. I get occasional flares here and there but nothing like it was.
That said, I'm curious if perhaps this is a reaction to Infliximab. I've been on it since 2018 and had been fine until May 2020. Also my UC has been under control since 2019 and I just stopped Imuran a few weeks ago. It's been since October since I've seen new hand sores and now I'm noticing a few more over the last week. I guess I'm just wondering if, by a long shot, anyone else had a similar experience or might have insight into what is going on. To me, it looks like my immune system is reacting to something but the doctors seem confident it's not the Infliximab. Anyways, if this sounds familiar to anyone, please let me know.