So regarding concern about
the bleeding. I was the one who asked what is riskier, being on Azathioprine and Mezavant like now and continued bleeding or being on steroids and/or Azathioprine + Humira.
therapeutic levels on aza, im on the max dose for my weight. 200mg. I weigh 80kg.
The question was regarding cancer risks mainly and I was told that usually its more of a risk when the colitis is extended, in my case it is the last 4cm.
Due to Covid and not being vaccinated yet, Biologic + Azathioprine is a lot riskier of course and another round of Prednisone is not a great solution either since it would be by 5th round. Ive only had to go up to 60mg twice before and that was a full blown 20 times a day diarreah flare, where there is usually no option but Prednisone.
I go 1-3 times a day, somedays none, I don't think this is sufficient to go on a high 60mg prednisone taper...a little excessive perhaps.
I have had tests every 3-4 months for the last 2 years since on Aza and levels are usual, obviously some metrics aren't because its a drug affecting it directly. My next one will be in a few months.
If I choose a biologic now, since I still have symptoms, it wouldn't be approved unless I was on Aza for a whole year in paralel, where's if there's no bleeding it may not have to be so long. These are rules within the health system where I live, Spain.
Why would I change to Humira if Im in remission? Well this is what I said before that docs seem to be preferring biologics to azathioprine since Covid because you are more prone to viruses with Aza than biologics it seems. so that would be why. And also if I can avoid taking 8 grams of pills everyday it would also be a benefit.
If Aza was working like it should, why would I be bleeding? Obviously something isn't right.
Biologic is probably the way I need to go but its just the combo right now seems risky without vaccination yet.
Post Edited (1Wish) : 5/8/2021 7:09:50 AM (GMT-6)