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Lutein Zanzeaxanthin anyone

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Ulcerative Colitis
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sailaway555
New Member
Joined : Mar 2021
Posts : 2
Posted 3/31/2021 8:33 AM (GMT -6)
Greetings,

I have lived with UC for over 30 years.

I had the side effects from steroids and the disease - bone degeneration, steroid induced cataracts, RA, fibromyalgia... but I have been able to avoid surgery except for hemroidectomy. I've had a heart attack and have CAD but still consider myself lucky. I had to retire a little early but can still do most of the things used to.

Currently Pentasa is the only prescribed medication I take for UC. I have been taking Lutein Zanzeaxanthin for the last several years and noticed I no longer had flares. The reason I started taking it was several articles about UC and increased risk for Macular Degeneration.

Has anyone else correlated the Lutein with an improved condition?

I had previously tried many things including Remicade which were little or no help.

Thanks,
Bill D
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naturalcurl
Regular Member
Joined : Nov 2010
Posts : 249
Posted 3/31/2021 6:19 PM (GMT -6)
I have taken Preservision, usually one a day, for a coupe of years. Lutein 5 mg; Zeaxeathin 1mg with no change in IBD symptoms. 2 per day recommended but the zinc makes me nauseated.
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KV18
Regular Member
Joined : Aug 2014
Posts : 98
Posted 3/31/2021 7:27 PM (GMT -6)
This is super interesting, and I will now try it! I did genetic testing recently for a variety of reasons and It was indicated I was at a high risk for IBD ( which I have lol) & Macular degeneration. I immediately booked a eye doc appt this week and I am totally going to trying taking this supplement you mention Lutein, what a bonus if it minimizes flaring lol, thanks for this. I'll report back on my experience.
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London Lurker
Veteran Member
Joined : Feb 2013
Posts : 1062
Posted 4/2/2021 4:30 AM (GMT -6)
It could just be that you are of the group for whom UC reduces with age but nonetheless, I have been meaning to look at supplements for this because Tim Spector (book - The Diet Myth), who has done a lot of research on nutrients is not a promoter of supplements at all has said that Lutein does seem to produce results. I think the action has something to do with blocking blue light so in our screen heavy world this could be even more important. However, looking at some more research it does seem to affect inflammation so it may well be helping.
I've been tracking my nutrient intake on cronometer and it always shows very low for lutein and zeaxanthin even though I'm eating a really varied diet at the moment.
" In vitro studies show that lutein suppresses NF kappa-B activation as well as the expression of iNOS and COX-2. Since AMD has features of a chronic low-grade systemic inflammatory response, attention to the exact role of lutein in this disease has shifted from a local effect in the eye towards a possible systemic anti-inflammatory function"
https://www.sciencedirect.com/science/article/abs/pii/s135094621200016x
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sailaway555
New Member
Joined : Mar 2021
Posts : 2
Posted 4/2/2021 6:53 AM (GMT -6)
I should have included the dosage and meds.
L-40mg - Z-2mg once daily but started with twice daily for 6 months until I noticed the palm of my hands turning yellow.
Pentasa 500mg 2 twice a day.
Omega 3 and B12
Calcium Citrate + D 600mg 3 times a day

Last colonoscopy a little over a year ago there was slight inflammation but I had tried to go completely off the Pentasa for a few months.

This all could be because I am changing with age but I don't think I will try going off the Lutein to test it. I had spent years stopping my meds when I felt better only to get hit for a long period of time.

I think some of the big external contributors for me were red meat, dairy, and caffeine.

bill
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