Posted 4/16/2021 3:43 PM (GMT -6)
I'm in an IBD/Covid group and we have had this conversation many times. The answer is, it depends on the person, so it's hard to know. They use steroids in some cases to help covid illness because sometimes the body's reaction to covid is what kills the person. The immune system just goes haywire. A lot of us with IBD have dysregulated immune systems. They are too strong or react to the wrong things.
Generally, prednisone is not considered a problem with covid. Other immune suppressants might be. The people who were on imuran in the group did not have more severe covid, but their covid tended to last longer. People who were already flaring tended to get slightly worse flares, maybe because covid also targets the bowels, but more likely because it triggers an inflammatory response and if you're already having one then it just adds to the pile.
The one thing that they aren't 100% sure about is long-term covid immunity while on immune suppression. A major study is currently being done in the UK on IBD patients on immune suppression who receive the vaccine, and their body's immune response. The results will be out in the autumn, if I recall right. It's possible that immune suppression prevents proper covid immunity from forming long-term, and this may have implications in how effective the vaccines are. For now, they are still vaccinating IBD patients and hoping for the best.
Over all, I would not worry too much.