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A Prednisone alternative without side effects?

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Ulcerative Colitis
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iPoop
Forum Moderator
Joined : Aug 2012
Posts : 16472
Posted 9/28/2021 6:46 AM (GMT -8)
This is a phase 1 clinical trial, but boy would it be nice to have something as effective as Prednisone without the side effects.

https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6136660/
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CCinPA
Veteran Member
Joined : Dec 2014
Posts : 2743
Posted 9/28/2021 8:46 AM (GMT -8)
That would be fabulous!!!!!!!
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momto2boys
Veteran Member
Joined : Jun 2013
Posts : 2625
Posted 9/28/2021 8:54 AM (GMT -8)
That would be a dream come true!
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Dandelion77
Regular Member
Joined : Nov 2017
Posts : 35
Posted 9/28/2021 8:58 AM (GMT -8)
This is fascinating and potentially very exciting. Thanks for sharing, ipoop!
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FlowersGal
Veteran Member
Joined : Feb 2017
Posts : 1826
Posted 9/28/2021 9:27 AM (GMT -8)
Sounds great. Only problem I foresee is it’ll be so darn expensive we won’t be able to afford to use it. (Big grrrr! at big pharmacy/insurance)
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quincy
Elite Member
Joined : May 2003
Posts : 33679
Posted 9/28/2021 9:28 AM (GMT -8)
Awesome!!
q
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Old Hat
Veteran Member
Joined : Feb 2007
Posts : 5923
Posted 9/28/2021 9:58 AM (GMT -8)
Vamorolone, eh? Interesting study, thanks for posting, ipoop. / Old Hat (40+ yrs with left-sided UC; in remission taking Colazal)
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Sara14
Veteran Member
Joined : Mar 2007
Posts : 7914
Posted 9/29/2021 8:44 AM (GMT -8)
Yes, please.
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brucen36
Regular Member
Joined : Mar 2014
Posts : 345
Posted 9/29/2021 10:13 AM (GMT -8)
Apparently, there's already trials for it in paediatric ulcerative colitis.
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VanJordan
Veteran Member
Joined : Dec 2019
Posts : 566
Posted 10/2/2021 6:26 PM (GMT -8)
I'm skeptical. There are always side effects, they just haven't fully discovered them yet.

They used pregnenolone before prednisone was discovered, and preg is much more gentle... and it's OTC to this day. They have to make new drugs to see profits, that's all.
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