Posted 10/16/2021 4:30 AM (GMT -7)
When there were only a couple biologic choices, they'd try and add imuran to the patient's maintenance meds, use IV solumedrol/prednisolone as a premed, and continue. Some posters here did that quite a number of years back. Honestly, can't remember how that went, maybe others do.
I'd say switching is the best thing to do these days. As you responded well on remicade, I'd ask about switching to one of its sister meds, humira or Simponi which use the same mechanism of action. They're molecular makeup is different enough that having antibodies to remicade is irrelevant.
High antibodies makes side effects like joint pains, rashes, fever temps, and other things higher. You're also higher odds of infusion reactions, like troubles breathing/swallowing, headaches, anaphylactic shock, etc. If resuming infusions I'd consider premed with solumedrol.