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crp 14 is high?

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Ulcerative Colitis
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Hambo88
Regular Member
Joined : Feb 2018
Posts : 226
Posted 1/6/2022 6:04 AM (GMT -7)
My crp is moving, i have inflamination this is sure but 14 is high?
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poopydoop
Veteran Member
Joined : Dec 2018
Posts : 1606
Posted 1/6/2022 6:20 AM (GMT -7)
depends what's "normal" for you and what the "normal" ranges are at the lab where you did the test. I've never had higher than 10mg/l, but my sister with crohns can go > 50 in a flare. (also, CRP is influenced by any kind of inflammation in the body, including infections or response to vaccines, if you've had any of those recently)
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Hambo88
Regular Member
Joined : Feb 2018
Posts : 226
Posted 1/6/2022 6:37 AM (GMT -7)
normal range is under 5...
i know this higher, but i dont that this is serious or this is a litle problem.
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poopydoop
Veteran Member
Joined : Dec 2018
Posts : 1606
Posted 1/6/2022 7:11 AM (GMT -7)
I don't know either. It's not especially high, but it's also higher than ideal. Could be caused by many factors, not just UC.
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damo123
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Joined : Jul 2007
Posts : 885
Posted 1/6/2022 10:26 AM (GMT -7)
CRP is recorded on different scales so you should always quote the units your measurement was given in usually either mg/l or mg/dl. If you do not then a reading of 14 could equally be interpreted as a reading of 140 by others.

CRP is plotted as a normal bell shaped curve for the entire population and the cut off point about what is considered high is then determined by labs to be the probability of getting a score in the upper 10% or 5% or sometimes 1% level. So some labs will have the cut-off at 3mg/l and others at 5mg/l etc. The cut-off point is not some magic level for which under the level you do not have inflammation and over the level you do. Rather the cut-off point refers to the spectrum of level your recorded value is in.

CRP is an acute phase reactant and is used as proxy to the amount of acute inflammation you have in your body relative to the normal population. For acute flare ups of inflammatory conditions it does give a good proxy as to where you inflammation status might be. For chronic low-grade inflammation quite frankly the measure is useless. Some people will not be "CRP producers" and so even with acute inflammation their levels will not rise above the norm or only just slightly above it. CRP can also be affected by other factors such as age, and overall health conditions most notably cardiac conditions.

Inflammatory conditions cannot be diagnosed by blood or stool tests. Rather such needs to be interpreted in the bigger picture and more broader sense by your physician. With all that said your value is tending to go high so it would imply there might be some acute inflammation present. But this needs to be interpreted relative to your current symptoms and health condition ideally by your doctor or nurse.

D
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