Posted 4/14/2022 3:13 PM (GMT -8)
I am currently tapering and at 25mg/day prednisone. I started at 40mg/day, and have been on high dose for about 4 years now. Asacol, imuran, entyvio, stelara, humira have all failed. I am currently getting inflectra and entyvio infusions, and taking imuran 200mg/day. Log story, and last effort with these biologics before trying Xeljanz.
The prednisone is a love/hate relationship for sure. I don't sleep well either, but my flare is stopped in its tracks. I have dealt with some pretty serious anxiety episodes, and probably close to psychosis a few times.
A normal taper for me has been to decrease by 5mg/day weekly.