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FDA Approves Rinvoq for Treatment of Ulcerative Colitis

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Ulcerative Colitis
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barnsbury
Veteran Member
Joined : Jan 2006
Posts : 526
Posted 4/11/2022 7:30 AM (GMT -8)
Not sure if already posted.

https://www.gastroendonews.com/FDA-Update-and-Product-News/Article/03-22/FDA-Approves-Rinvoq-for-Treatment-of-Ulcerative-Colitis-/66495
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quincy
Elite Member
Joined : May 2003
Posts : 33636
Posted 4/11/2022 8:48 AM (GMT -8)
Made the link live.


https://www.gastroendonews.com/fda-update-and-product-news/article/03-22/fda-approves-rinvoq-for-treatment-of-ulcerative-colitis-/66495

q
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ks1905
Veteran Member
Joined : Sep 2005
Posts : 6411
Posted 4/11/2022 9:07 AM (GMT -8)
My GI told me there was two new biologicals that were supposed to be approved soon, I guess it was this one and the other one is supposed to be Skyrizi for Crohn's (he mentioned that one by name).
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poopydoop
Veteran Member
Joined : Dec 2018
Posts : 1964
Posted 4/11/2022 9:11 AM (GMT -8)
rinvoq (upadacitinib) is from the JAK-inhibitors family (same as xeljanz/tofacitinib and filgotinib), so I'm guessing your GI might mean another drug?
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ks1905
Veteran Member
Joined : Sep 2005
Posts : 6411
Posted 4/11/2022 9:17 AM (GMT -8)

poopydoop said...
rinvoq (upadacitinib) is from the JAK-inhibitors family (same as xeljanz/tofacitinib and filgotinib), so I'm guessing your GI might mean another drug?

I'm not sure, I could have interchanged biological with new drugs. I just asked him if there was any new meds coming on the market soon. He mentioned Skyrizi by name and that there were two drugs being approved by the FDA in the next month or two. I didn't pay too much attention because I am doing well on my current medication.
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straydog
Forum Moderator
Joined : Feb 2003
Posts : 19563
Posted 4/11/2022 12:52 PM (GMT -8)
We have a member on here that is on Rinvog & a biologic. I cannot remember the username, so far this member is having success. And the member is getting the two meds from two different drs that are working together. Strange situation, one dr is in NY & the other one is out of the country.

I did some digging, Hugo18 is taking Rinvog daily, Stelara monthly.
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Hugo18
Regular Member
Joined : Mar 2017
Posts : 299
Posted 4/12/2022 11:05 AM (GMT -8)
Not really that "strange" of a situation. It is from the same doctor but was attained via two different opinions.
It combines stelera with rinvoq. Seems to do a great job for now.
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Sara14
Veteran Member
Joined : Mar 2007
Posts : 7914
Posted 4/13/2022 6:15 AM (GMT -8)
Great news. Thanks for sharing.

"Corticosteroid-free clinical remission was reported for 57% and 68% of patients treated with 15 or 30 mg, respectively, versus 22% of the placebo group, in the maintenance trial."

Those are pretty good stats.
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madampoopsalot
Regular Member
Joined : Jan 2018
Posts : 122
Posted 4/14/2022 8:14 AM (GMT -8)
Any one know if someone could have success with one JAK inhibitor but not another? Just curious for now, but about to start Xeljanz (maybe)
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Hugo18
Regular Member
Joined : Mar 2017
Posts : 299
Posted 4/14/2022 9:50 AM (GMT -8)
Well Xeljanz worked well for me until it started working and now Rinvoq, which is a JAK seems to be doing the job. Same family but slightly different types of mechanisms.
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