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complex relation of exercise to UC flares

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Ulcerative Colitis
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ilovefood
Regular Member
Joined : Dec 2010
Posts : 139
Posted 5/3/2022 5:35 AM (GMT -8)
Hi all,

By doing searches, I see there have been some threads in the past on this. But it's a topic that doesn't get so much discussion, so I thought I'd add another based on my experience this spring.

Clearly, exercise can have real and important benefits for UC. Studies have shown this, I believe. But it also does seem, based on my own and others' experiences, that because of the immune system component, over-exertion can also lead to a flare. It's a delicate balance.

This spring I had an arm injury and had to stop my regular resistance exercises. As I gradually increased the amount I was doing with my arms in PT, I began adding some of my old leg/core exercises back in during the same sessions. The PT arm stuff had by that time gotten quite intense, and adding the other exercises on top of them seemed to trigger a flare.

Now, as I am fighting the flare off (with more rectal meds), I find that if I overdo it with the exercises, I have a bad day afterward, but if I do a more moderate workout, it creates immediate improvement. This has now happened multiple times and I don't think it's coincidence. (I was also a fanatical aerobics exerciser when first diagnosed in my 20s.)

I am someone who, more generally, will get cold symptoms the next day if I overexert myself. So I think that there is a way in which my immune system gets easily over-triggered by exercise. Does anyone else have this reaction?

Again, I want to stress here that an appropriately challenging but not too extreme workout is, I think, very beneficial for UC. But all this is suggesting to me that exercise may be a complex issue for (at least some) IBDers.
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UCinsouthfl
Regular Member
Joined : Mar 2014
Posts : 194
Posted 5/4/2022 11:07 AM (GMT -8)
Hi,

I've had UC for about 10 years.

I've always been a huge gym goer. I feel 10 times better when exercising regularly. At the same time I have often wondered the same thing as you regarding exercise. (There are some studies that suggest the same.)

There was a time when I was convinced that over exertion from extreme exercise played a role. Now I'm not so sure. (Except when I do Crossfit, this kills me!) This disease is so tricky, because I logically want to believe that these different things trigger symptoms, but the longer I deal with it, I just don't know.

I know this isn't the answer you want to hear, because we want hard facts, so we can better deal with our condition. All we get all the time is "Its different for everyone". (I'm sorry. Today I'm a little frustrated with my UC too.)

I hope you find answers and I'd also like to hear what other have to say about it.

Currently failing remicade. On 10mg/kg every 4 weeks, 10mg of prednisone, hydrocort enema's nightly, and 150mg of Azathioprine.
Failed all mesalamines. 6mp. Simponi, Entyvio & Humira
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FlowersGal
Veteran Member
Joined : Feb 2017
Posts : 1635
Posted 5/5/2022 9:27 AM (GMT -8)
I can relate to this! After two years of heavy stress from my mothers dementia decline and then a 3 week intense stress as she passed, I went to get back on with my life and decided to go to a Piyo class. Thought it would be really easy as I’d done yoga for years, but OMG that class almost killed me and I was too self conscious to leave. That was a Saturday and Tuesday morning I woke up to bloody diarrhea and my eventual UC diagnosis. Probably a combo of the prolonged stress and the extreme (to me anyway) physical stress.
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VanJordan
Veteran Member
Joined : Dec 2019
Posts : 566
Posted 5/6/2022 12:33 PM (GMT -8)
It depends on frequency and intensity. Too much exercise increases oxidation status, which leads to excess hydrogen peroxide production in the cells, which is more than likely the root cause of UC. Conversely, exercise increases lymphatic drainage, detox pathways, and endocrine function, all of which tend to be low in UC.

So it's a delicate balance.

When I exercise regularly, especially weight lifting, I make sure I increase my anti-oxidant intake by a lot.
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ilovefood
Regular Member
Joined : Dec 2010
Posts : 139
Posted 5/6/2022 1:55 PM (GMT -8)
Hi Van, I’d be curious what the increasing of antioxidants looks like for you!
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Hambo88
Regular Member
Joined : Feb 2018
Posts : 257
Posted 5/6/2022 2:54 PM (GMT -8)
there is a study that the resistance trainibg decrease the ROS ( ROS cause big problem in UC)
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ilovefood
Regular Member
Joined : Dec 2010
Posts : 139
Posted 5/6/2022 2:56 PM (GMT -8)
What does ROS stand for?
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Hambo88
Regular Member
Joined : Feb 2018
Posts : 257
Posted 5/8/2022 5:55 AM (GMT -8)

VanJordan said...
It depends on frequency and intensity. Too much exercise increases oxidation status, which leads to excess hydrogen peroxide production in the cells, which is more than likely the root cause of UC. Conversely, exercise increases lymphatic drainage, detox pathways, and endocrine function, all of which tend to be low in UC.

So it's a delicate balance.

When I exercise regularly, especially weight lifting, I make sure I increase my anti-oxidant intake by a lot.

what kind of antioxidant do you eat?
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Hambo88
Regular Member
Joined : Feb 2018
Posts : 257
Posted 5/8/2022 5:58 AM (GMT -8)
for example c vit cause me sometimes bowel problem....
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quincy
Elite Member
Joined : May 2003
Posts : 33538
Posted 5/8/2022 8:28 AM (GMT -8)
Vitamin C can cause loose stool...comes in handy during constipation type phase of flaring....just adjust the dosage.

q
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Sara14
Veteran Member
Joined : Mar 2007
Posts : 7651
Posted 5/20/2022 6:58 PM (GMT -8)
I could never tell for sure. I used to be a marathon runner and even ran some ultras (50 miles once and once 68). I never flared after the marathons but did after both ultras. But I wasn't in solid remission back then either, and I also was sleep-deprived, skipped my rectal meds the days of those races, etc. And I was actually already mildly flaring before the 68 mile race but all hell broke loose shortly after. I remember getting flare symptoms while training heavily (lots of miles) as well but again, I was only on mesalamine back (with prednisone needed usually once or twice a year) then and rarely felt like I was in solid remissions. If I ever get back to running much now while on Xeljanz, it'll be interesting to see what happens. However, I don't know that I'll ever be able to run as much as I used to after all those years of steroids, considering I've now had 2 stress fractures in my foot just from walking.:/

I get cold symptoms sometimes the day after not getting enough sleep, which I always found odd.
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