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Van Jordan

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Ulcerative Colitis
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Posted 6/8/2022 1:24 PM (GMT -8)

VanJordan said...

Hambo88 said...
I think Dr. Pravda will not reveal his medicine free of charge what there are in his method, because as i red right he has a patent for this method.
I would be suprised if he would write into the next paper what kind antioxidant they have used.
But i am not expert of this issues and the habits regarding the studies.

I would very happy if he would write an article about his method but he could do it till now.

His media all says that another paper is forthcoming. I don't doubt that's true. I also highly doubt he is going to charge people money to reveal the medicine. His research is all independent (but peer reviewed) from what I can tell, which means he is doing this for other reasons than money.

How do you propose he would keep his treatment secret, anyway? As soon as a group of people are treated, they're going to tell others what happened.

Please be patient and don't be so negative.


i am positiv, basically my attitude is positiv smile but realistic is the most of the time.
no problem we will see what happen i hope he will share all the details which help us a lot.
As i know this kind of researches are going on with code names of the medicines/ suplements. So if i would be part this kind of study i would receive the xgrk4574 medicine, as i know this is working in this way, but maybe i am wrong?
Van Jorden otherwise thanks to you too for all the information what you have shared here regarding this topic and congrstulation that you have developed your own healing way and you have reached remission.
Posted 6/9/2022 4:12 AM (GMT -8)
maybe do you know the Briggs protocol? this protocol also based on oxidativ stress theory.( this is only additional information)
Posted 6/9/2022 8:39 AM (GMT -8)
"The medications I use to treat ulcerative colitis are all approved for or naturally found in the colon and are administered together, once daily, for 4-6 weeks. Each component serves a different purpose, all aimed at reducing colonic hydrogen peroxide regardless of the extent and severity of the colitis. Remission is maintained by modest dietary and lifestyle changes that prevent the production of excess cellular hydrogen peroxide. This therapeutic mechanism of action is evidence-based and well-tolerated."

This is so frustrating. He's basically saying: Well I have a potential solution but I'm not telling you. He said he's tried to reason with CCFA but they won't listen. Some patients can't "be patient." Would there be legal repercussions if he did so without a paper to back it up? Are we still waiting on a paper? Is he even conducting a study? Is this all wishful thinking? I do see the point that if this was all true and hydrogen peroxide is the cause, that would really rattle the mesalamine/biologic/etc industry b/c they are making bajillions off us.
Posted 6/9/2022 10:19 AM (GMT -8)

DavidEA said...
"The medications I use to treat ulcerative colitis are all approved for or naturally found in the colon and are administered together, once daily, for 4-6 weeks. Each component serves a different purpose, all aimed at reducing colonic hydrogen peroxide regardless of the extent and severity of the colitis. Remission is maintained by modest dietary and lifestyle changes that prevent the production of excess cellular hydrogen peroxide. This therapeutic mechanism of action is evidence-based and well-tolerated."

This is so frustrating. He's basically saying: Well I have a potential solution but I'm not telling you. He said he's tried to reason with CCFA but they won't listen. Some patients can't "be patient." Would there be legal repercussions if he did so without a paper to back it up? Are we still waiting on a paper? Is he even conducting a study? Is this all wishful thinking? I do see the point that if this was all true and hydrogen peroxide is the cause, that would really rattle the mesalamine/biologic/etc industry b/c they are making bajillions off us.


I had the same question. Why we have to wait? if it is 100% solution. But if this is the solution and this therapy can be cure everybody the other biliogy therapy producers will lose very very big money!!!!!
Because more thousand, million people who suffer by Uc , crohn will be cured. This company' s losses will be billion dollars.

if i know well, mesalamin is one of the strongest antioxidant? why can not it help? why can not kill the hydrogen peroxide? it is only a question.

I hope very much this hydrogen peroxide theory is the root cause, i am on my own therapy.

VAN JORDAN: when did you noticed the first sign that you are improving when you start your theraphy?
Posted 6/9/2022 9:11 PM (GMT -8)

Theanxiousaries said...
I found this https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804255/

I did notice I felt better from half of the scoop provided.
The brand I use is https://cell-logic.com.au/
I will buy the other when I use all this one

A cursory look seems to indicate that the product you're using is on the higher end.

When I first started taking sulforaphane capsules, I had to take 1/5th of the capsules because the changes in my gut flora were too radical and gave me symptoms. Now I take two of the BROCQ capsules twice a day. I plan to continue for 6 months and then I'm going to remove the supplements one by one and see what happens.
Posted 6/9/2022 9:17 PM (GMT -8)

DavidEA said...
"The medications I use to treat ulcerative colitis are all approved for or naturally found in the colon and are administered together, once daily, for 4-6 weeks. Each component serves a different purpose, all aimed at reducing colonic hydrogen peroxide regardless of the extent and severity of the colitis. Remission is maintained by modest dietary and lifestyle changes that prevent the production of excess cellular hydrogen peroxide. This therapeutic mechanism of action is evidence-based and well-tolerated."

This is so frustrating. He's basically saying: Well I have a potential solution but I'm not telling you. He said he's tried to reason with CCFA but they won't listen. Some patients can't "be patient." Would there be legal repercussions if he did so without a paper to back it up? Are we still waiting on a paper? Is he even conducting a study? Is this all wishful thinking? I do see the point that if this was all true and hydrogen peroxide is the cause, that would really rattle the mesalamine/biologic/etc industry b/c they are making bajillions off us.

I realize it's frustrating, but my understanding is that he has had to conduct this research independently because of lack of support from the major Crohn's/Colitis organizations and big pharma. I don't know the full story, I just know that it's slow going.

One of his studies *did* mention what he used, things like butyric acid, budesonide, DHLA, etc. He is definitely working on another paper, so hang tight. He probably won't mention a lot of specifics until he has a lot more data. Remember, everything claimed in peer reviewed research must be proven and reproducible. That's a lot to take on as an independent investigator.

The interesting thing about mesalamine is that it probably works because it directly reduces extracellular hydrogen peroxide that has leaked into the bowel. It is an acid, after all. The problem is that it can't address the hydrogen peroxide production *within* cells that eventually leaks out into the extracellular colonic environment. So it's topical only.

I do have my concerns that if Pravda has really found the golden arrow, big pharma will try to bury him. They do that with a lot of promising discoveries. However, they can't put that genie back in the bottle. A lot of people have read Pravda's studies and antioxidants are abundant in the world around us. Big pharma can't get rid of them all. The problem is going to be convincing GI doctors that this is real. They are all super loyal to the pharmaceutical-industrial complex, by training and funding. They are trained to dismiss almost everything if big pharma research hasn't told them it's correct.
Posted 6/9/2022 9:27 PM (GMT -8)

Hambo88 said...
I had the same question. Why we have to wait? if it is 100% solution. But if this is the solution and this therapy can be cure everybody the other biliogy therapy producers will lose very very big money!!!!!
Because more thousand, million people who suffer by Uc , crohn will be cured. This company' s losses will be billion dollars.

if i know well, mesalamin is one of the strongest antioxidant? why can not it help? why can not kill the hydrogen peroxide? it is only a question.

I hope very much this hydrogen peroxide theory is the root cause, i am on my own therapy.

VAN JORDAN: when did you noticed the first sign that you are improving when you start your theraphy?

As mentioned above, Pravda is doing all of his research independently. His discovered the hydrogen peroxide connection on his own, without any help from big institutions. That's why they won't support him... because they can't profit off of his discovery. Just as a side note, I have to say, most of the best alternative cures I have ever read about have been discovered this way: highly trained but independent thinkers who went off and researched what they wanted, rather than only researching what big pharma told them to research. They get ignored because they won't play the profit game. Before all research became privatized, it was done the way Pravda is doing it. A team would be given a bunch of public funding and they would go off to make discoveries with no profit motive. The loss of public research is why nothing is being cured anymore.

The Crohn's MAP vaccine being trialed in the UK right now was also funded purely independently. Big pharma would have nothing to do with it, likely because it could very well cure or at least significantly downgrade a lot of Crohn's symptoms. They are in phase 3 trials right now if I recall correctly, or about to be. I can't wait to read the results of that study!

Mesalamine is topical only. It can neutralize hydrogen peroxide that has already leaked into the colon, but it can't enter the cells to neutralize it at its source. It also has expicents (ingredients) that are intolerable to some, so the colon is exposed to irritating ingredients in addition to the active medical ingredient. I can't personally tolerate mesalamine, it makes my inflammation and bleeding explode. I think it may be because it's too acidic, but I'm not sure. While it may neutralize hydrogen peroxide, for those of us with severe UC, it may be too corrosive to our severely raw rectums. It's a derivative of salicylic acid which is known to cause gut corrosion, which is why they reformulated to mesalamine to make it less caustic. However, I think even mesalamine is too caustic for some of us.
Posted 6/9/2022 9:31 PM (GMT -8)

Hambo88 said...
maybe do you know the Briggs protocol? this protocol also based on oxidativ stress theory.( this is only additional information)

I found the Briggs protocol useless. It still relies on immune suppression as a first line treatment. In my opinion, the oxidative stress of moderate to severe UC cannot be fixed by diet alone, even if the diet is very anti-oxidant rich. In order to break the vicious cycle, really concentrated forms of anti-oxidants need to be introduced to the body. Food forms are too dilute. That's why the Briggs protocol is another failure. That protocol is also unaware of hydrogen peroxide as the root cause, so they don't even know what they're aiming for.

That's why I find Pravda's discovery revolutionary. When you KNOW it's H2O2, you can stop trying to aim at a moving target and finally pare down your protocols. Knowing the root cause has been such a relief to me. Not knowing that information made treating this condition endlessly frustrating.
Posted 6/9/2022 11:31 PM (GMT -8)

Somebody said...
Before all research became privatized, it was done the way Pravda is doing it. A team would be given a bunch of public funding and they would go off to make discoveries with no profit motive. The loss of public research is why nothing is being cured anymore.

Not ALL research is privatised. Public funding is still available. Would be great to have more public funding of course but then you'd have to change the whole political system (and have more public respect for scientists etc etc).
Posted 6/10/2022 10:51 PM (GMT -8)

poopydoop said...
Not ALL research is privatised. Public funding is still available. Would be great to have more public funding of course but then you'd have to change the whole political system (and have more public respect for scientists etc etc).

You're correct, but the public funding is usually small time. Big pharma has lobbied to have laws altered so that the requirements of research and development cost hundreds of millions of dollars, so that non-private sources can't compete. It has severely restricted avenues of investigation.
Posted 6/15/2022 7:53 AM (GMT -8)
Would you mind posting what amount you take of each every day? I am not seeking medical advice, I am just curious what has been working for you.

I found a product called Xhumanx sulphoraphane on Amazon. There are 60 capsules at $29.95, Each serving 2 capsules. They claim it contains 10mg of sulphorphane plus some other ingredients per serving. So about $1.00 for a 10 mg dose.
The BROCq brand has 20mg of sulphorphane in a serving of 2 capsules. That one works out to $4.96 per (20 mg) serving or $2.48/10mg to compare to the HumanX brand.
So the xHumanx brand is quite a bit cheaper. I have no idea if quality is the same. Just thought I'd pass that along.https://smile.amazon.com/gp/product/B08B5LFVJW/ref=ppx_yo_dt_b_search_asin_title?ie=UTF8&psc=1

VanJordan said...
These are the products I take:

Grape Seed Extract:
https://www.amazon.com/Olympian-Labs-Extract-capsules-bottle/dp/B000UZUAFA/ref=sr_1_46?crid=1ULNRUHBG7G5&keywords=grape+seed+extract&qid=1654401259&sprefix=grape+seed+ex%2Caps%2C335&sr=8-46

Sulforaphane:
https://www.amazon.ca/BROQ-Sulforaphane-Supplements-Independent-Stabilized/dp/B08JG27DSZ

Curcumin:
https://www.amazon.com/Thorne-Research-Meriva-500-Phytosome-Supplement/dp/B005P0UF4Q/ref=sr_1_3?crid=2KJMJFYJC6RU3&keywords=thorne+SF&qid=1644365218&sprefix=thorne+sf%2Caps%2C161&sr=8-3
You need to take sulforaphane, not broccoli seed extract. The best one on the market that I know of is called BrocQ and it's on Amazon.

Butyrate:
https://www.amazon.com/Tesseract-Medical-Research-ProButyrate-Bio-Availability/dp/B075BRR1JJ

For quercetin, any brand will do. Same with vitamin C and rutin. They are very common.

BROQ has increased in price *a lot* and I'm not sure why. I am investigating a new sulforaphane supplement now. Even though the protocol is pricey, you don't have to be on it forever. Once the gut heals and seals (usually 6 months), you can revert to maintenance or periodic doses. I also take vitamin E and camu camu, which are very high in antioxidants.

Dr. Pravda does not generally respond to patients because his primary focus is research. He will publish a new paper in the not too distant future that will detail a more refined protocol than his previous papers. For example, his last paper required rectal administration, but I have not used any rectal meds in this protocol.

I have refractory UC and working with his theory put me into remission within 6 weeks after being prednisone dependent for 2.5 years. Nothing else worked. I have been doing a lot of ancillary research related to oxidative stress and the whole thing just explains UC so well. In the years I've had UC, I've done dozens of different protocols, thousands of hours of research, and experimented on myself like crazy. Nothing has been so surefire as this protocol. There is no doubt in my mind that the reductive theory of UC (hydrogen peroxide) is correct.

Even if Pravda's research doesn't lead to product development to help UC, it doesn't matter... we know the root cause now. It's oxidative stress. Lifestyle, diet and supplements that maximally target cellular oxidation will make UC go away. We just need to develop the best strategies for doing so!

Posted 6/15/2022 11:28 AM (GMT -8)
Grapeseed extract:
I took 400mg/day from the first day.

Curcumin (must be phytosomal/meriva):
500mg twice daily

Sulforaphane:
I started by dividing a 20mg capsule and took 1/5th a capsule per day. Eventually I worked my way up to a single 20mg daily. Sulforaphane is powerful and causes changes to the gut flora, so you want to proceed gradually.

Tesseract Probutryate:
1 capsules 2x daily from the very beginning.

I also take whole spectrum vitamin E in the form of rice bran. 1 teaspoon with breakfast. Vitamin E is another powerful antioxidant. I also take whole food forms of vitamin C: camu powder, rosehip powder, or acerola cherry powder. Do not take ascorbic acid, it is not fully functional vitamin C. Whole food C regenerates the body's antioxidants much more effectively. The bioflavonoids also feed beneficial cut flora.

EDIT:
Sorry, I forgot to mention:
Rutin - 50-100mg/day
Quercetin - 250mg/day
Posted 6/15/2022 7:03 PM (GMT -8)
Thank you so much, appreciate it.
Posted 6/15/2022 9:04 PM (GMT -8)
i have tried another therapy, Dr. Datis Kharrazian made it but the principles similar like dr. Pravda' s studies.

This therapy aim is also boosting the glutathion production. He also suggest to use dhla which has been mentioned in dr. Pravda's studies.

I have been take these supplement and as i think dhla 600 mg cause me diarhea. This is an acid, when i took 200 mg i had not any problem but but dr. Pravda suggest 600 mg in his study then i lifted to it.

Maybe i also make a trial with Van Jorden's supplements.
Posted 6/15/2022 9:21 PM (GMT -8)

Hambo88 said...
i have tried another therapy, Dr. Datis Kharrazian made it but the principles similar like dr. Pravda' s studies.

This therapy aim is also boosting the glutathion production. He also suggest to use dhla which has been mentioned in dr. Pravda's studies.

I have been take these supplement and as i think dhla 600 mg cause me diarhea. This is an acid, when i took 200 mg i had not any problem but but dr. Pravda suggest 600 mg in his study then i lifted to it.

Maybe i also make a trial with Van Jorden's supplements.

What brand of dhla are you using?
Posted 6/16/2022 12:27 PM (GMT -8)
i have 2 types. I have 250 mg pill from BiotechUSA. And i have 100 mg version from Swanson.

I take also NAC, guta kola, cordyceps.
Posted 6/16/2022 6:17 PM (GMT -8)
I think I’ll add one thing at a time. I’m still struggling to increase the broccoli extract. I can handle cabbage juice though and I also get formed stools after cabbage juice. It also had glutamine in it
Posted 6/16/2022 6:47 PM (GMT -8)

Theanxiousaries said...
I think I’ll add one thing at a time. I’m still struggling to increase the broccoli extract. I can handle cabbage juice though and I also get formed stools after cabbage juice. It also had glutamine in it

Broccoli seed extract is not the same thing as sulforaphane. Don't confuse the two.
Posted 6/16/2022 6:49 PM (GMT -8)

Hambo88 said...
i have 2 types. I have 250 mg pill from BiotechUSA. And i have 100 mg version from Swanson.

I take also NAC, guta kola, cordyceps.

BiotechUSA and Swanson only sell ALA. That is not the same thing. People with UC should not take ALA, it will make them worse.
Posted 6/16/2022 8:21 PM (GMT -8)
you are right DHLA= R-Dihydro-Lipoic Acid
What i am taking is ALA=alpha lipoic acid.

I did not think this difference is important sad How did u know that this version is not good for UC patient.

and thank you for your help.

I had same problem with c vit.
I caused me diarrhea. ( 1000 mg)
Posted 6/16/2022 10:09 PM (GMT -8)
Van Jordan you take the rice bran on cereal (not rice bran oil?
Posted 6/17/2022 12:23 AM (GMT -8)

Hambo88 said...
I did not think this difference is important sad How did u know that this version is not good for UC patient.

I explained this in another thread at great length so I don't want to repeat it too much here. Basically, ALA is the oxidized version of lipoic acid. The body has to use its antioxidant resources to convert it to the non-oxidized form in order to use it properly. In doing so, the body sacrifices antioxidant capacity that it could be using to neutralize hydrogen peroxide in the colon. So the hydrogen peroxide problem gets worse. People with UC already have abnormally high oxidative stress. We can't afford to lose anymore antioxidant capacity on reducing ALA from its oxidized form to its antioxidant form.

UC patients should only take antioxidants. Any supplement that is in the oxidized form will make the hydrogen peroxide problem worse.
Posted 6/17/2022 12:25 AM (GMT -8)

Theanxiousaries said...
Van Jordan you take the rice bran on cereal (not rice bran oil?

This is one example of rice bran:
https://cdn.shopify.com/s/files/1/0516/8103/4398/products/Natural_Traditions_Rice_Bran_and_Germ_Solubles_By_Organic_Traditions_Canadian_front_of_bag_image_1400x_2fe434b0-bc8e-4981-b950-d0882d5d622a.png?v=1643399190

I usually just eat a tea spoon with water and chew it, but some people put it into things like cereal. It doesn't matter, really.

Rice bran oil is good but I don't use it because it's expensive.
Posted 6/17/2022 4:45 AM (GMT -8)
I thought all forms of sulforaphane were broccoli extract. I’ve never seen a supplement that’s not isolated from broccoli seeds
Posted 6/17/2022 6:00 AM (GMT -8)

VanJordan said...

Hambo88 said...
I did not think this difference is important sad How did u know that this version is not good for UC patient.

I explained this in another thread at great length so I don't want to repeat it too much here. Basically, ALA is the oxidized version of lipoic acid. The body has to use its antioxidant resources to convert it to the non-oxidized form in order to use it properly. In doing so, the body sacrifices antioxidant capacity that it could be using to neutralize hydrogen peroxide in the colon. So the hydrogen peroxide problem gets worse. People with UC already have abnormally high oxidative stress. We can't afford to lose anymore antioxidant capacity on reducing ALA from its oxidized form to its antioxidant form.

UC patients should only take antioxidants. Any supplement that is in the oxidized form will make the hydrogen peroxide problem worse.

how can i recognize this difference? For example if i bought a selenium or c vit or any other how can i recognize which is the right form for the uc patient which is the "not oxidized" form...?

Post Edited (Hambo88) : 6/18/2022 11:59:20 PM (GMT-6)

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