Biopsy results

You're within a remission, no active inflammation found. Congrats!

Chronic architectual changes to your cells is noted on the left-side only. So, your historic extent of your UC is limited to your left -side only. That's sigmoid colon and above it. No symptoms from architecture changes, it's like a fingerprint or identifier that you are an IBD patient. Normal horizontal across your belly button and normal right side of the large intestine.

I'd ask your doctor about 2 points:

1.) Scattered mucosal lymphoid nodules with germinal center formation are present. It can be signs of a past infection. It's likely nothing but it's there in your report so I'd follow up on it.

2.) Ask about the anal biopsy pointing toward a low grade dysplasia (precancerous changes). It's likely something they'll just monitor in future endoscopy, and nothing to worry about now. I'd just bring that up as a point of discussion and verify it's nothing to be worried about.

3.) Yes, there were no architecture changes noted in your rectum. Likely that's deeply healed and hasn't seen inflammation in a long time. Cells are replenished over long timeframes, erasing some architecture changes.

Congrats!! You're remission is confirmed by the biopsies. Rest easy, Sarah ... you can exhale So happy for you!!

Says mild chronic inflammation, but NOT active colitis...that's confusing to me
If the architectural changes stated consistent with mild chronic inflammation, that would make sense. Are you still on oral mesalamine?

I don't know about lymphoid nodules except they seem to be associated with infection of some kind (from what I read)....

Yes...you needed that lesion removed since it was HPV associated and presented with dysplasia.

All in all...looks like a great report. Can you use the enemas at this point?

q

I'm not in full remission according to my GI. Thank God I have him and didn't just listen to the surgeon (have I mentioned I hate her? Lol).

This is what he said after reading the biopsy report:
"This is pretty good. The biopsies of the left colon (descending and sigmoid), which includes the splenic flexure showed very mild inflammation. The degree of inflammation seems to be very minimum because it doesn't mention acute inflammatory changes."

Asked him about the lymphoid node thing in a followup message.

Anyway, I'll take this result and be pleased with it. Lol.

He said all colons have lymph nodes and that part is nothing to worry about...

My opinion...definitely into and above the sigmoid. How far would depend on how much stool is in the colon at the time. What dosage of delzicol are you on?
I also suggest fibre supplement and probiotics...

Im glad the GI clarified...because remission isn't what I see. You are doing well, however. Did you have an infection not that long ago?

q

Thanks, q. I'm still on 4800 mg Delzicol but I miss some doses so should probably not do that anymore. I wasn't quite as vigilant with it as I used to be since feeling well on Xeljanz.

Not sure about the infection. I thought it might be a possibility a month or 2 ago because I had diarrhea and some other pretty mild symptoms but all the stool samples came back negative for infections. I had a full work up. My calpro was pretty high. I upped my xeljanz dose for 3 weeks. My symptoms went away. I had been back down to lower dose for 10 days at time of scope. I don't really understand his comment about the lymph nodules. I guess I'll be forever confused.

I saw some old post from you when looking up propofol. I hate propofol and they keep pushing it on me in recent years, even when I tell them what it does to me after it wears off (massive anxiety including intrusive suicidal thoughts, sobbing all night, no appetite....this time I felt drunk almost all day and evening). I just got ALL my old records and did well on versed and fentanyl in the past. Do you still request only fentanyl?

Flowers: Thanks. Good to know it can happen. Next time I will just have an actual GI do the scope. Im trying to find someone local again, at least for scopes, but healthcare seems pretty hit or miss where I live currently. This was an odd situation and I had a colorectal surgeon do it. Her written report says mild erythema but she told me she saw nothing which is weird because my GI said that note usually means inflammation. I feel fairly informed but the path reports still confuse me at times. And hearing different explanations from different doctors doesn't help! Then I try to Google things and sometimes confuse myself more. But thank god the internet and this forum exists so we can do our own research.

Thanks. I'm not letting one more anesthesiologist force me to get propofol ever again. It also makes the cost $400-500 higher for the patient because the doctor himself can push versed...no need for an anesthesiologist.

They told me they injected some local anesthetic at the surgery site. I don't know what it was. It didn't last long because I could feel it on the drive home already. But not bad pain, pretty mild. Last 2 scopes prior they pushed propofol on me hard too. Next time I will be more assertive on not wanting that.