The finding of granulomas in the biopsies is a strong signal that this is likely Crohn's and not UC.
The history and symptoms you describe (more constipation than diarrhea, mucus, and not all that frequent blood in stool, the longstanding belief it was IBS instead of IBD) also indicate Crohn's is likely.
In that case, the mesalamines like Lialda wouldn't have done much if any good for you anyway.
Since Crohn's disease is highly suspected, you should have further testing to help solidify the diagnosis and to assess the condition of of the other regions of your digestive tract. This means having a small bowel MRI or CT scan with contrast.
Also, the joint pains and tailbone pain and uveitis mean you should have a workup done with a rheumatologist. They may be secondary to your IBD (ie, extra-intestinal manifestations), but they also might be signs that you have a separate rheumatologic condition.
After all this, an appropriate treatment plan can be formed.
Steroids are to be avoided when at all possible and only used as a last resort when symptoms are flaring badly and you need to get the symptoms under control quickly.
Stelara works for both Crohn's and UC, and for some rheumatologic conditions, so it's a reasonable choice given what you know. But as I stated above, further testing should be done.
Post Edited (beave) : 1/6/2023 12:26:14 PM (GMT-8)