Open main menu ☰
HealingWell
Search Close Search
Health Conditions
Allergies Alzheimer's Disease Anxiety & Panic Disorders Arthritis Breast Cancer Chronic Illness Crohn's Disease Depression Diabetes
Fibromyalgia GERD & Acid Reflux Irritable Bowel Syndrome Lupus Lyme Disease Migraine Headache Multiple Sclerosis Prostate Cancer Ulcerative Colitis

View Conditions A to Z »
Support Forums
Anxiety & Panic Disorders Bipolar Disorder Breast Cancer Chronic Pain Crohn's Disease Depression Diabetes Fibromyalgia GERD & Acid Reflux
Hepatitis Irritable Bowel Syndrome Lupus Lyme Disease Multiple Sclerosis Ostomies Prostate Cancer Rheumatoid Arthritis Ulcerative Colitis

View Forums A to Z »
Log In
Join Us
Close main menu ×
  • Home
  • Health Conditions
    • All Conditions
    • Allergies
    • Alzheimer's Disease
    • Anxiety & Panic Disorders
    • Arthritis
    • Breast Cancer
    • Chronic Illness
    • Crohn's Disease
    • Depression
    • Diabetes
    • Fibromyalgia
    • GERD & Acid Reflux
    • Irritable Bowel Syndrome
    • Lupus
    • Lyme Disease
    • Migraine Headache
    • Multiple Sclerosis
    • Prostate Cancer
    • Ulcerative Colitis
  • Support Forums
    • All Forums
    • Anxiety & Panic Disorders
    • Bipolar Disorder
    • Breast Cancer
    • Chronic Pain
    • Crohn's Disease
    • Depression
    • Diabetes
    • Fibromyalgia
    • GERD & Acid Reflux
    • Hepatitis
    • Irritable Bowel Syndrome
    • Lupus
    • Lyme Disease
    • Multiple Sclerosis
    • Ostomies
    • Prostate Cancer
    • Rheumatoid Arthritis
    • Ulcerative Colitis
  • Log In
  • Join Us
Join Us
☰
Forum Home| Forum Rules| Moderators| Active Topics| Help| Log In

Got a Q to HUMIRA users

Support Forums
>
Ulcerative Colitis
✚ New Topic ✚ Reply
❬ ❬ Previous Thread |Next Thread ❭ ❭
profile picture
WayneTX
Regular Member
Joined : Feb 2020
Posts : 105
Posted 2/7/2023 3:19 PM (GMT -8)
I was diagnosed with a severe case of UC at Dallas VAMC.......Gastrologist put me on 4 MESALINE tablets a day for about 6 months and they did another colonoscopy and that diagnose revealed that I had actually worsen so they decide to put me on HUMIRA pen injections in the stomach, which I began last month. I have injected two doses already 14 days apart. I am hoping this solves my issues as I am already a prostate cancer survivor so additional inflammation going on can not be a good thing. My questions are (1) has anyone taking HURIMA been able to get UC under control, and (2) is this truly a life-long treatment situation requiring injections every 2 weeks. Thank you in advance for any replies.
profile picture
CCinPA
Veteran Member
Joined : Dec 2014
Posts : 2518
Posted 2/7/2023 3:52 PM (GMT -8)
1) There are some with UC who have had success with Humira, but it seems to be more successful for Crohn's than UC
2) UC is life long and will require some form of ongoing treatment for life

Do you know what the dosage is of the pens you are using? When you first start you should have higher dosages the first few injections:
Day 1: 160 mg (single dose or
split over two consecutive days)
Day 8: 80 mg
Day 15: 80 mg
Then after that it should be
80 mg every other week
or
40 mg every week

Those higher loading doses in the first couple weeks are important to give Humira a kick start. If you did not do loading doses like described above, please ask your doc about that as soon as possible.

If you don't see significant improvement in your symptoms within 3 months it's doubtful this is the med for you and you should work with your doc to try a new med. Unfortunately, for many of us it's trial and error until we find the medication that gets us to remission. UC is a very individual disease in that what works for one person may not work for others.

My best advice is to read all you can about UC and the various treatments so you can partner with your doctor to arrive at what works best for you. With this disease it truly does require a good doctor/patient partnership. Don't be afraid to ask questions and advocate for yourself. Remember: you have only one patient to treat (yourself). Your doc likely has hundreds so his attention is going to be split in many directions.

There is a lot of good info on this forum. I know I learned a LOT about UC here. My docs never really explained much and there were some meds (rectal meds) I would never have known about if not for Healing Well. I had to ask my doc to prescribe them. Generally, we hear about new treatments here before our doctors even know about them.

(Congrats on surviving prostate cancer!)
profile picture
straydog
Forum Moderator
Joined : Feb 2003
Posts : 19333
Posted 2/7/2023 8:35 PM (GMT -8)
Welcome to the forum Wayne TX. You have landed at a good place to ask questions. I have crohns & joined HW back in 03. I learned more about crohns here at HW than any dr could have told me. In fact my gi suggested I find a good online support forum. Careful where you read or what you read, lots of bad information out there.

Humira is one of the older drugs, originally approved for crohns, but later approved for UC like so many other drugs. Hopefully once you get to the therapeutic range you will start seeing improvement. I would expect some improvement at 3 months, but certainly not remission by then. When my gi starts his patients on a new medication he has a 6 month rule unless there is zero improvement or the patient becomes worse. You will find each dr has their own protocol. The good news is if for some reason Humira doesn't work out there are many other medications to try.

As CC mentioned, UC is life long & you will need to be on treatment the rest of your life. Newbies sometimes decide to stop their medication once they start feeling better, that's denial kicking in. Don't let yourself go down that rabbit hole because it's tough making another comeback. Get in remission & live your life.

Take care.
profile picture
ld2186
Regular Member
Joined : Aug 2018
Posts : 51
Posted 2/11/2023 7:35 AM (GMT -8)
I did well for several years on Humira. I had to increase the dose to weekly injections, but overall it was a good med for me. I stopped in 2022 because of side effects and have now switched to Entyvio.
I hope Humira works for you!
profile picture
Rusty Barr
Regular Member
Joined : Feb 2016
Posts : 407
Posted 2/11/2023 8:19 AM (GMT -8)
I was on Humira for 4 years and it worked great. Then I got pneumonia and I came off it per the ER doctors instructions. After I got over the pneumonia I was still in remission with my IBD. I asked my (then) GI if I could just stay off it, and that maybe I was in complete remission and didn’t need to be on any drug any more. He said, ok, I don’t recommend it, but let’s give it a go.

about 8 months later I started to flare. He put me back on it. It didn’t work. I had built up antibodies to it.
He said, oh yeah, that can happen if you stay off it a long time.

I was not happy! Had he told me this when I first asked about staying off it I might have went right back on it.
Knowing how well it worked for me, and knowing that IBD is a chronic life long illness.

Anyway. Moral of the story and why I am posting in this thread….

If you go on it and it works…stay on it
✚ New Topic ✚ Reply


More On Ulcerative Colitis

November Is Crohn's & Colitis Awareness Month

November Is Crohn's & Colitis Awareness Month

Ambushed From Within: Ulcerative Colitis - The Other IBD

Ambushed From Within: Ulcerative Colitis - The Other IBD


HealingWell

About Us  |   Advertise  |   Subscribe  |   Privacy & Disclaimer
Connect With Us
Facebook Twitter Instagram Pinterest LinkedIn
© 1997-2023 HealingWell.com LLC All Rights Reserved. Our website is for informational purposes only. HealingWell.com LLC does not provide medical advice, diagnosis, or treatment.