I am on entyvio and now see blood at 7th week.
Have you finished your loading doses? Were you on pred during the loading doses? If the answer to both questions, give it more time. Enyvio is slower to kick in than other meds. I think I was told to allow 3 months to see improvement and longer to reach full remission. How are your other symptoms?
I always thought of Entyvio as the "safer" biologic because it was specifically developed for UC and targets the colon. All the other biologics and jak inhibitors are more systemic. I don't know of any that have psoriasis as a side effect, but there could be some. Most were developed for either arthritis or psoriasis and then eventually got approved for UC.
I went from Entyvio to Humira and now infliximab (Remicade/Inflectra). I loved Entyvio but it only worked for me for about
a year. Humira never really worked.. Infliximab got me functional pretty quickly, but it took almost 2 years with dose changes until I reached remission.