NSAIDs

nanrush

New Member

Joined : Jul 2007

Posts : 10

Posted 8/15/2007 4:09 AM (GMT -7)

Hi all:

Does anyone know how damaging these meds are to the colon? I used to take them for years before I knew I had UC. Now I'm really afraid of them.

Thanks all.

Nancy

Diagnosed 7/07 due to ER visit and hospitalization

Meds: Asacol 400 mg. - 3 x day, Rowasa 1 x day

probiotics, digestive enzymes, diet changes

Biggest No No - NSAIDS

Have Lupus, total knee replacement, osteo

Red_34

Forum Moderator

Joined : Apr 2004

Posts : 23569

Posted 8/15/2007 4:33 AM (GMT -7)

I used to take them frequently too before my Uc diagnosis. Now I won't touch them at all because it makes me flare. But Nsaids promote bleeding in our intestines. If you think about it, most docs will tell you to stop all Nsaids a week or so before surgery because it can cause bleeding complications during surgery. Any sort of med that can do this will also increase the risk for us since our colons bleed so easily anyway. Also you should avoid all prescription anti inflammatories as well as anything that can thin the blood.

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SPB

New Member

Joined : Aug 2007

Posts : 16

Posted 8/15/2007 5:38 AM (GMT -7)

When I get a chance I'll look for it but there are articles contending that the studies linking NSAIDs to UC troubles are flawed. Basically, the main study that "shows" this link asked hospitalized UC sufferers if they had used NSAIDs in the previous ___ weeks. People eat these things like candy, so of course there's a link. It's a tenuous connection.

The same MD who tells you not to take NSAIDs will swear that antibiotics aren't going to cause you any undue GI stress. I know better than that.

I've found the best rule of thumb is to use what you've alwyas used and keep an eye on it. I like and still use aspirin.

Another UC wife

Veteran Member

Joined : Jun 2007

Posts : 2111

Posted 8/15/2007 6:12 AM (GMT -7)

My husband's VA doctor told him a month or so ago to absolutely stop taking the ibuprofen and the indomethacyn that he would take off an on that seemed to help him due to their anti inflammatory properties. He takes an 81 mg baby aspirin each day that was not eliminated as part of his medicine routine. NSAID's are a no no I guess due to what is posted above.

60 yr old male~Colitis 1st diagnosed Jan '05-cleared up within a few wks. Flared again in May '06 ... left sided ulcerative colitis now & fully involved and trying to get in remission. Acute inflammation-pancolitis-tenesmus rectal pain-granulation is showing some healing started. Osteopena of spine from prednisone DX 8/07 July 07 starting to feel somewhat normal 75mg Imuran 40 mg prednisone (tapering 8/07) 12 Asacol, Lidocaine Hydrochloride Jelly 2%,multi vitamin, iron 3X day, DanActive, chewable calcium, Prilosec 20mg, enalapril 10mg, glipizide 5 mg, zocor 20 mg, baby aspirin, (Fentanyl pain patch 50mg 72 hrs Morphine Sulf 15 mg twice daily)Colocourt enemas at night.

quincy

Elite Member

Joined : May 2003

Posts : 31152

Posted 8/15/2007 8:48 AM (GMT -7)

I take aspirin for headaches (since I was a kid) and have the "OK" from my GI reluctantly...but he drew the line at ibuprophen.

I do bruise more when I take too much aspirin. I need to see the chiro more often methinks.

quincy

*Heather*Status:mini flare June 23* 6asacol daily+ Salofalk (tapered every 3rd night)

~diagnosed January 1989 UC (proctosigmoiditis)

~5ASA: Asacol + Salofalk enemas (increase for flares tapered to maintenance)

~Bentylol (dicyclomine) 20mg as needed

~vitamins/minerals

~Probiotic 2 (Natural Factors Protec) + 1 (Primadophilus Reuteri) at bedtime

~Natural Factors Multi Digestive Enzymes with supper

~Ranitidine,Pariet (reflux) Effexor XR 75mg; Pulmicort/Airomir (asthma)

~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)

My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!

nanrush

New Member

Joined : Jul 2007

Posts : 10

Posted 8/16/2007 2:19 AM (GMT -7)

Thanks for replies. I now take tylenol and only hope they're OK.

Diagnosed 7/07 due to ER visit and hospitalization

Meds: Asacol 400 mg. - 3 x day, Rowasa 1 x day

probiotics, digestive enzymes, diet changes

Biggest No No - NSAIDS

Have Lupus, total knee replacement, osteo

SPB

New Member

Joined : Aug 2007

Posts : 16

Posted 8/16/2007 3:42 AM (GMT -7)

Tylenol is recommended, but I've found it doesn't do much for me. As with all OTC pain killers, I'd caution against using too much, especially Tylenol. It's kind of mindboggling how many people overdose on acetominophen every year and they often don't know it until they need a liver transplant.

quincy

Elite Member

Joined : May 2003

Posts : 31152

Posted 8/16/2007 9:17 AM (GMT -7)

The liver/tylenol connection is definitely something for us to be aware of....definitely.....but if we are taking much more than we need, maybe it's time to seek other meds/methods to supplement the regimen to help keep the pain in check.

q

*Heather*Status:mini flare June 23* 6asacol daily+ Salofalk (tapered every 3rd night)

~diagnosed January 1989 UC (proctosigmoiditis)

~5ASA: Asacol + Salofalk enemas (increase for flares tapered to maintenance)

~Bentylol (dicyclomine) 20mg as needed

~vitamins/minerals

~Probiotic 2 (Natural Factors Protec) + 1 (Primadophilus Reuteri) at bedtime

~Natural Factors Multi Digestive Enzymes with supper

~Ranitidine,Pariet (reflux) Effexor XR 75mg; Pulmicort/Airomir (asthma)

~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)

My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!

SPB

New Member

Joined : Aug 2007

Posts : 16

Posted 8/16/2007 9:29 AM (GMT -7)

quincy said...
The liver/tylenol connection is definitely something for us to be aware of....definitely.....but if we are taking much more than we need, maybe it's time to seek other meds/methods to supplement the regimen to help keep the pain in check.

q

Absolutely. For intense, chronic pain, I'd say one is better off with an opioid than Tylenol. (Although, yes, you have to worry about having your bowel stall on those.)

pb4

Elite Member

Joined : Feb 2004

Posts : 20577

Posted 8/16/2007 10:20 AM (GMT -7)

It's been proven that NSAIDS do promote bowel bleeding and that's why any good GI will warn their patients to avoid them.

:)

My bum is broken....there's a big crack down the middle of it! LOL :)

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