Asacol vs. Colosal?

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Regular Member

Date Joined Aug 2007
Total Posts : 277
   Posted 8/20/2007 9:42 AM (GMT -6)   
Anyone had better luck with one med over the other?  Ive been on asacol 16 yrs, during this flare he switched me to colozal just to see what woiuld happen....I dont know yet cuz im not over this flare yet.
UC diagnosed 1991
Asacal, Coloazal, prednisone 50, adding zoloft..currently flaring

Elite Member

Date Joined Apr 2004
Total Posts : 23551
   Posted 8/20/2007 10:13 AM (GMT -6)   
I was on Asacol for 12 years and even though it helped, eventually my body just couldn't take it anymore. So my doc switched me to Colazal too. I found that it helped me in the beginning but now I think my body is having the same reaction to when I was on Asacol. Some people do respond better to one over the other. It may take a few weeks before you notice the difference though.
Left sided Uc since '92 - meds - Colazal, Canasa (when needed), 6MP (50-75mgs), Forvia, Biotin (IN REMISSION - sort of!)
Secondary Raynauds Syndrome '04  - meds - Norvasc
Fibromyalgia '06 - no meds
Severe seasonal allergies - meds - Allegra 
@--->--Moderator for Allergies/Asthma and Co-moderator for UC--<---@


Veteran Member

Date Joined Dec 2006
Total Posts : 3670
   Posted 8/20/2007 12:22 PM (GMT -6)   

Me, I've done asacol and had great results BUT the side effects, tiredness, lips felt like blisters and I'm sure others I can't think of but these were the main two was cauesed by Asacol

I'm on colozal and no problems whatsoever! I feel great on it. I realized what was making me tired was taking Vitamin B that had valerian root in it. I used it to relax my nerves.

I like colozal a lot! I take 2 pills twice a day.

I had the Rocephin shot and 2 weeks of Omnicef, this helped with my bloating and digestion. That was 4/15/07
Had Cipro and Predison for 10 & 5 days, 7/3/07
colonoscopy & Endoscopy 7/27, Left sided colitis
Colozal 4 a day

Veteran Member

Date Joined Jul 2005
Total Posts : 514
   Posted 8/20/2007 3:12 PM (GMT -6)   
Colozal didn't do a thing for me. I took 9(and those pills are HUGE) pills a day for month and didn't notice any change. I took Asacol for the first time during my last flare, thought it wouldn't work at all, and I started feeling better 12 hours after taking it and it got me back in remission. I only take 6 a day and they are tiny! All the 5-ASAs are bascially the same med, but are released based on the PH in your colon, so one drug MAY work for you while another won't.
Officially Diagnosed with UC in June 2003.  Have had stomach issues since 1989.  Unknown if they are related or not.  Have mild/moderate UC.  Have had 4 flares, the last one caused by hormones from stopping breastfeeding.  Currently back in remission!  Only taking 6 Asacol a day.   Will take Rowasa enemas as needed. Colozal did not work for me.  Luckily my UC is relatively minor and responds well to meds, but man do those flares hurt!

Old Hat
Veteran Member

Date Joined Feb 2007
Total Posts : 5191
   Posted 8/20/2007 3:25 PM (GMT -6)   
They have different bonding agents so that one may agree with some patients better than the other. Colazal agrees with me better than Azulfidine, Asacol, or Dipentum & therefore gives me a better  chance to stay in remission than these older 5-ASAs. / Old Hat (nearly 30 yrs with left-sided UC; currently on 3 X 3 Colazal daily for July flare in descending colon, which is responding)

lil slowpoke
Regular Member

Date Joined Sep 2006
Total Posts : 290
   Posted 8/20/2007 6:38 PM (GMT -6)   
Asacol gave me reflux, I am happier on colazal, and my colon is quieter.
uc since feb '05
colazol 9 day, calcium, multivitamin, fishoil
atenolol, bc pills, b-2, b-6 ( for migraine relief)
stonyfield farm yogurt
in remission

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