Hi There - my husband started the Imuran along with prednisone to help it "kick in" (I realize you can't tolerate the prednisone)
That was 3 1/2 months ago - and we are tapering the prednisone - it is helping and working but he is not in a true remission as he still needs pain meds to be functional. I understand it can take 3-6 months to work.
However the advice of a few on this board about
the rectal meds.....we started them on June 26th and on July 2nd there was a noticeable improvement. The improvement was such that he went from a total recluse with uncontrollable urges and living in the bathroom and bed to being able to go out for a few hours and socialize which was a major thing. We would be careful about
food before going out - made sure he ate first - spent some time in the house and use the bathroom before going out. While out and needing to eat making sure it was smaller amounts and not be too far from home.
My husband uses Colocourt. There are others out there and the doctor should know which would be best to prescribe for you. Hopefully you can retain it for at least 2 hrs before having to dispel it or part of it as most of the medicine would be absorbed. My husband had a problem holding them for many hours but after 2 - 3 hours due to gas primarily he would go to the bathroom but there was very little coming out as it was only the gas so he was absorbing most of the medicine. Maybe they will provide some additional help and comfort for you until the imuran takes a better hold. Hopefully it won't be too long for you.
60 yr old male~Colitis 1st diagnosed Jan '05-cleared up within a few wks. Flared again in May '06 ... left sided UC now, fully involved and trying to get in remission. Acute inflammation-pancolitis-tenesmus rectal pain-granulation is showing some healing started. Osteopena of spine from prednisone DX 8/07 July 07 good days & bad days 75mg Imuran 40 mg prednisone (tapering 8/07) 12 Asacol, Lidocaine Hydrochloride Jelly 2%,multi vitamin, iron 3X day, DanActive, chewable calcium, Prilosec 20mg, enalapril 10mg, glipizide 5 mg, zocor 20 mg, baby aspirin, (Fentanyl pain patch 50mg 72 hrs Morphine Sulf 15 mg twice daily)Colocourt enemas at night. Fosamax and mthly B12 shots folic acid 1mg