Colazal Side Effects

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Regular Member

Date Joined Jul 2007
Total Posts : 26
   Posted 9/7/2007 3:00 PM (GMT -6)   
Has anyone had any side effects from Colazal?

Veteran Member

Date Joined May 2006
Total Posts : 619
   Posted 9/7/2007 4:02 PM (GMT -6)   
None whatsoever, and I got side effects from almost everything else I tried. It did not get me into remission, but when I went off it things got worse, so it definitely has made a difference. Compliance has been an issue, but I set my PDA to remind me to take my afternoon dose, I take the other doses at wake-up and at bedtime, so that's been working out. I can even swallow all three of those horse pills at the same time now!

Diagnosed UC April 27, 2006
Remicade: 1st infusion 7/21/07; 2nd infusion 8/18/07
Prednisone 4/27/06-present; failed at every taper attempt until Remicade infusion. Currently alternating 10 mg/5 mg on alt days; Colazal three 750 mg capsules 3X day; Protonix;
Xanax; Rowesa; Asacol; [2/22/07 started Imuran, off within two weeks due to bad reaction]

Old Hat
Veteran Member

Date Joined Feb 2007
Total Posts : 5182
   Posted 9/7/2007 7:03 PM (GMT -6)   
Colazal has been more helpful/tolerable for me than any of the older 5-ASAs. One side effect I did get around 10 weeks into 3 X 3 capsules daily: AM dizziness. We had a thread about this in March or April; I remember that DallasGuy complained about dizziness, too. My gastro decided that I could try a so-called "step-up, step-down approach" to see if lower dose Colazal would keep me in remission. It did for 20 months w/o side effects. / Old Hat (nearly 30 yrs with left-sided UC; currently on 3 X 3 Colazal daily for July flare in descending colon; should be back in remission soon)

Forum Moderator

Date Joined Apr 2004
Total Posts : 23551
   Posted 9/7/2007 8:03 PM (GMT -6)   
When I first started it I had a floating feeling and headaches. But after my body got used to it, all was fine.

Meesh, it's funny you mentioned the 3 in one swallow now. I do the same thing but one morning, I took my 3 Colazal, Forvia vitamin, biotin and a Prilosec all in one mouthful and swallowed before I realized what I did! lol Luckily I didn't choke!

Left sided Uc -'92 - Colazal, Canasa, 6mp, Prilosec, Biotin, Forvia
Secondary Reynauds Syndrome - '04 - Norvasc
Fibromyalgia - '06 
@--->--Moderator for Allergies/Asthma and Co-moderator for UC--<---@


lil slowpoke
Regular Member

Date Joined Sep 2006
Total Posts : 290
   Posted 9/8/2007 11:56 AM (GMT -6)   

I love the colazal.I think my stools are softer because of it, but that's fine with me, and it may just be my new normal.

 I get then down three at a time with rarely a problem.

Sherry, you got away with it because you weren't thinking about it!

I've taken 3 colazal and two small b vitamin capsules at once. It does get easier.
uc since feb '05
colazol 9 day, calcium, multivitamin, fishoil
atenolol, bc pills, b-2, b-6 ( for migraine relief)
stonyfield farm yogurt
in remission

Regular Member

Date Joined Jun 2007
Total Posts : 20
   Posted 9/9/2007 11:14 AM (GMT -6)   
Colazal has worked wonders for me. I have noticed that my stools have been softer, and I find that I'm incredibly tired most of the time. I'm not sure if the tiredness is a side effect of the Colazal or if it's just caused by my UC, but given how much better it's made me feel, I deal with it.
-25 year old female with left-sided UC and ulcerative proctitis
-Diagnosed May 2004, in remission for four months currently
-Past medications: Rowasa, Canasa, Dipentum, Asacol
-Current meds: Colazal 9 pills a day (finally off prednisone--yayy!), Flora-Q, multi-vitamin

Veteran Member

Date Joined Dec 2005
Total Posts : 3238
   Posted 9/9/2007 12:51 PM (GMT -6)   
My stools are definitely softer on Colazal. Besides that no side effects for me.....and I typically get every side effect known to man!
Tabitha (Tab)

100mg Azathioprine, 2 Fibercon, Colazal-6 a day, Acidopholis Pearls, Prilosec OTC
Co-Moderator UC Forum

Regular Member

Date Joined Jul 2007
Total Posts : 262
   Posted 9/10/2007 7:29 AM (GMT -6)   
Lots of farts...
Male 36yrs old. Indeterminate Colitis 6 yrs.

100 mg 6-mp
Lialda 2 a day

multi vitamin

Regular Member

Date Joined Sep 2006
Total Posts : 246
   Posted 9/10/2007 11:21 AM (GMT -6)   
nothing that im aware on 6/day but lately have been alternating between 5 and 6 as im mostly in remission
- 29 y/o male living in the DC Metropolitan region
- UC diagnosed - April, 2006 - symptoms came on sudden
- GI could not determine type of UC as I was too inflamed during the colonoscopy
- Completed 3rd Prednisone taper on 4/13/07 - Tapered from early January through mid-April after being hospitalized from a bad flare with anemia & severe joint pain.
- Currently in remission
- 6 Colazal/day, 1 Multivitamin, Fish oil, Primal Defense Probiotics 2/day, Iron supplement when bleeding
- Use small dose (5-10mg) of prednisone occassionally to manage joint pain

Regular Member

Date Joined Dec 2006
Total Posts : 89
   Posted 9/11/2007 4:43 AM (GMT -6)   
No side effects, but I'm not sure it's actually done anything for me either.

Regular Member

Date Joined Sep 2004
Total Posts : 51
   Posted 9/11/2007 1:48 PM (GMT -6)   
I tried taking Colazal early in my diagnosis, but my symptoms got measureably worse (I was already flaring with d, bleeding, cramps...), so my GI said I was probably having a reaction to the carrier in it. I've never tried it since....about 5 years ago.
36 yr old female
Diagnosed 7/2002
Currently taking:
Asacol:  6 pills/2 X a day
Canasa:  as needed
Super B Complex Vitamins
Flinstones Complete
Calcium 1000 mg/day

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